Results 241 to 250 of about 50,405 (295)

Pulmonary light chain deposition disease secondary to Sjögren disease: a case report. [PDF]

open access: yesFront Immunol
Xu X   +7 more
europepmc   +1 more source

Evaluation of vaccine-induced antibody responses against SARS-CoV-2 in multiple myeloma patients from the northeastern region of Mexico. [PDF]

open access: yesHematol Transfus Cell Ther
Salazar-Riojas R   +6 more
europepmc   +1 more source

Teclistamab Treatment Followed by Heart Transplantation for Advanced Immunoglobulin Light Chain Amyloid Cardiomyopathy. [PDF]

open access: yesJACC Case Rep
Ibrahim M   +10 more
europepmc   +1 more source

Truncation of the constant domain drives amyloid formation by immunoglobulin light chains [PDF]

open access: yesJournal of Biological Chemistry
AL amyloidosis is a life-threatening disease caused by deposition of immunoglobulin light chains. While the mechanisms underlying light chains amyloidogenesis in vivo remain unclear, several studies have highlighted the role that tissue environment and ...
Antonino Natalello   +2 more
exaly   +4 more sources
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Immunoglobulin light chains, glycosaminoglycans, and amyloid

Cellular and Molecular Life Sciences, 2000
Immunoglobulin light chains are the precursor proteins for fibrils that are formed during primary amyloidosis and in amyloidosis associated with multiple myeloma. As found for the approximately 20 currently described forms of focal, localized, or systemic amyloidoses, light chain-related fibrils extracted from physiological deposits are invariably ...
Robert Kisilevsky, Fred J Stevens
exaly   +3 more sources

Immunoglobulin light chain amyloidosis

Expert Review of Hematology, 2013
Primary light chain amyloidosis is the most common form of systemic amyloidosis and is caused by misfolded light chains that cause proteotoxicity and rapid decline of vital organ function. Early diagnosis is essential in order to deliver effective therapy and prevent irreversible organ damage.
MERLINI, GIAMPAOLO   +4 more
openaire   +3 more sources

Light chain immunoglobulins as substrates for collagenase

Immunochemistry, 1975
Abstract The proteolytic action of collagenase on immunoglobulin light chains has been studied by mean of quantitative determination of N-terminal amino acid residues. L (λ) and L (κ) appear to be susceptible to the enzymatic action and this characteristics is a highly specific and general one.
M A, Coletti-Previero   +2 more
openaire   +2 more sources

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