Pulmonary light chain deposition disease secondary to Sjögren disease: a case report. [PDF]
Xu X +7 more
europepmc +1 more source
Evaluation of vaccine-induced antibody responses against SARS-CoV-2 in multiple myeloma patients from the northeastern region of Mexico. [PDF]
Salazar-Riojas R +6 more
europepmc +1 more source
Teclistamab Treatment Followed by Heart Transplantation for Advanced Immunoglobulin Light Chain Amyloid Cardiomyopathy. [PDF]
Ibrahim M +10 more
europepmc +1 more source
Truncation of the constant domain drives amyloid formation by immunoglobulin light chains [PDF]
AL amyloidosis is a life-threatening disease caused by deposition of immunoglobulin light chains. While the mechanisms underlying light chains amyloidogenesis in vivo remain unclear, several studies have highlighted the role that tissue environment and ...
Antonino Natalello +2 more
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Immunoglobulin light chains, glycosaminoglycans, and amyloid
Cellular and Molecular Life Sciences, 2000Immunoglobulin light chains are the precursor proteins for fibrils that are formed during primary amyloidosis and in amyloidosis associated with multiple myeloma. As found for the approximately 20 currently described forms of focal, localized, or systemic amyloidoses, light chain-related fibrils extracted from physiological deposits are invariably ...
Robert Kisilevsky, Fred J Stevens
exaly +3 more sources
Immunoglobulin light chain amyloidosis
Expert Review of Hematology, 2013Primary light chain amyloidosis is the most common form of systemic amyloidosis and is caused by misfolded light chains that cause proteotoxicity and rapid decline of vital organ function. Early diagnosis is essential in order to deliver effective therapy and prevent irreversible organ damage.
MERLINI, GIAMPAOLO +4 more
openaire +3 more sources
Usefulness of Bcl-2 Expression and the Expression of Cytoplasmic Immunoglobulin Light Chains in the Differentiation Between B-Cell Lymphoma and Reactive Lymphocytic Proliferations in FNA [PDF]
Simon Bucek +2 more
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Light chain immunoglobulins as substrates for collagenase
Immunochemistry, 1975Abstract The proteolytic action of collagenase on immunoglobulin light chains has been studied by mean of quantitative determination of N-terminal amino acid residues. L (λ) and L (κ) appear to be susceptible to the enzymatic action and this characteristics is a highly specific and general one.
M A, Coletti-Previero +2 more
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