Results 11 to 20 of about 601,756 (240)
IntroductionImmunoglobulins (Igs) play a pivotal role in host defense and prevention of pneumonia. Aging influences serum Ig levels, but the association between Igs and pneumonia in community-dwelling older individuals remains unknown.
Samer R. Khan +16 more
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Doxycycline-resistant Scrub Typhus in a Syndromic Child [PDF]
Scrub Typhus, a human febrile illness caused by Orientia tsutsugamushi, is common in Asia and infects persons those visiting the endemic areas. Scrub typhus is a zoonotic infection. It is transmitted by a trombiculid mite which introduces the bacteria by
Priya Margaret +2 more
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The effect of basketball competition on resting level of Immunoglobulins in elite female basketball players [PDF]
This research aimed to investigate the effect of one period of first division basketball competitionon some immune system factors in elite female basketball players.
محمد فرامرزی +2 more
doaj +1 more source
Characterization of B1-cells during experimental leukomogenesis
Background. Bovine leukemia causes a significant polyclonal expansion of CD5+ , IgM+ B lymphocytes, known as persistent lymphocytosis (PL), in approximately 30% of infected cattle.
I. Yu. Ezdakova +3 more
doaj +1 more source
Diagnosis of toxoplasmosis by joint detection of immunoglobulin A and immunoglobulin M [PDF]
An indirect immunofluorescence test with total anti-human immunoglobulin conjugate (IgG,A,M-IIF) can be used for joint detection of immunoglobulin A (IgA) and IgM antibodies, provided serum IgG is previously absorbed with anti-human IgG. To determine the validity of the IgG,A,M-IIF assay with absorbed sera, the results obtained were compared with those
Gloria Griemberg +2 more
openaire +3 more sources
Validation of Roche immunoassay for severe acute respiratory coronavirus 2 in South Africa
Background: Serology testing is an important ancillary diagnostic to the reverse transcriptase polymerase chain reaction (RT-PCR) test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Jurette S. Grove +12 more
doaj +1 more source
Toxoplasmosis in immunoglobulin M-suppressed mice [PDF]
Mice challenged with a pathogenic strain of Toxoplasma gondii develop fatal infections. However, if such mice are initially treated with sulfadiazine (SD), they develop immunity and survive with chronic infections. The role of antibody (Ab) in establishing protective immunity against acute parasitemias and in maintaining chronic infections was ...
Frenkel, J K, Taylor, D W
openaire +2 more sources
Aim: As the primary response antibody with increasing use as a therapeutic immunoglobulin (Ig) format, IgM is also the largest antibody structure among the five major human isotypes. Spontaneously formed pentamers and hexamers of IgM have avidity effects
Wei-Li Ling, Samuel Ken-En Gan
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Update on the hyper immunoglobulin M syndromes [PDF]
SummaryThe Hyper‐immunoglobulin M syndromes (HIGM) are a heterogeneous group of genetic disorders resulting in defects of immunoglobulin class switch recombination (CSR), with or without defects of somatic hypermutation (SHM). They can be classified as defects of signalling through CD40 causing both a humoral immunodeficiency and a susceptibility to ...
E. Graham Davies, Adrian J. Thrasher
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Non-functional immunoglobulin G transcripts in a case of hyper-immunoglobulin M syndrome similar to type 4 [PDF]
86% of immunoglobulin G (IgG) heavy-chain gene transcripts were found to be non-functional in the peripheral blood B cells of a patient initially diagnosed with common variable immunodeficiency, who later developed raised IgM, whereas no non-functionally
Allen RC +9 more
core +3 more sources

