Results 141 to 150 of about 655,587 (248)

Prognostic Significance of Lymphatic Vessel Invasion and Density in Colorectal Carcinoma: A Systematic Review and Meta-analysis. [PDF]

open access: yesCancer Diagn Progn
Varvarousis DN   +7 more
europepmc   +1 more source

PAX2 Loss by Immunohistochemistry Occurs Early and Often in Endometrial Hyperplasia

open access: green, 2012
Kimberly H. Allison   +7 more
openalex   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

open access: yesAdvanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo   +6 more
wiley   +1 more source

Diagnostic immunohistochemistry for canine cutaneous round cell tumours — retrospective analysis of 60 cases

open access: gold, 2015
Katarzyna Paździor‐Czapula   +4 more
openalex   +2 more sources

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

open access: yesAdvanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu   +14 more
wiley   +1 more source

The Need for Standardization of PRAME Immunohistochemistry in Melanocytic Neoplasms. [PDF]

open access: yesDermatopathology (Basel)
Sullivan CM   +6 more
europepmc   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

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