Immunohistochemistry in cutaneous pathology [PDF]
, 1983 J Thivolet, Michel Faure
openalex +1 more source
FEBS Open Bio, Volume 15, Issue 5, Page 836-855, May 2025.Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy +14 more
wiley +1 more source
Quantifying Smooth Muscles Regional Organization in the Rat Bladder Using Immunohistochemistry, Multiphoton Microscopy and Machine Learning [PDF]
arXivThe smooth muscle bundles (SMBs) in the bladder act as contractile elements which enable the bladder to void effectively. In contrast to skeletal muscles, these bundles are not highly aligned, rather they are oriented more heterogeneously throughout the bladder wall.
arxiv
Generalizing multistain immunohistochemistry tissue segmentation using one-shot color deconvolution deep neural networks [PDF]
arXiv, 2018 A key challenge in cancer immunotherapy biomarker research is quantification of pattern changes in microscopic whole slide images of tumor biopsies. Different cell types tend to migrate into various tissue compartments and form variable distribution patterns. Drug development requires correlative analysis of various biomarkers in and between the tissue
arxiv
Angiogenesis and Vasculogenesis at 7-Day of Reperfused Acute Myocardial Infarction [PDF]
, 2008 Objectives This study is to investigate the angiogenesis and vasculogenesis at the first week of reperfused acute myocardial infarction (AMI). Methods 16 of mini-swines (20 to 30 Kg) were randomly assigned to the sham ...
Qing-zhi Wang +6 more
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Assessment of tumor cell kinetics by immunohistochemistry in carcinoma of breast [PDF]
, 1987 John F. McGurrin +5 more
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FEBS Open Bio, EarlyView.We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei +6 more
wiley +1 more source
Virtualization of tissue staining in digital pathology using an unsupervised deep learning approach [PDF]
arXiv, 2018 Histopathological evaluation of tissue samples is a key practice in patient diagnosis and drug development, especially in oncology. Historically, Hematoxylin and Eosin (H&E) has been used by pathologists as a gold standard staining. However, in many cases, various target specific stains, including immunohistochemistry (IHC), are needed in order to ...
arxiv
Giant-celled glioblastoma of brain. A clinico-pathological and radiological study of ten cases (including immunohistochemistry and ultrastructure) [PDF]
, 1989 Jeffrey C. Margetts +1 more
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Establishment and biological characterization of radioresistant colorectal cancer cell lines
FEBS Open Bio, EarlyView.Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu +10 more
wiley +1 more source