Results 181 to 190 of about 963,734 (335)

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

Advanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen, Yingjie Fan, Tomas Germanas, Langston Tillman, Jinhong Li, Abigail L. Blenko, Ralph R. Weichselbaum, Wenbin Lin   +7 more
wiley   +1 more source

A Case of Nasal Malignant Lymphoma Confirmed by Immunohistochemistry

, 1988
N. Matsumoto, Hiroyuki Sugihara, Hitoshi Saitô, Kenji Saito, Gota Tsuda, Masaki Mori, Norio Miyoshi, Masaru Fukuda   +7 more
openalex   +2 more sources

Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases

Advanced Materials, EarlyView.
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu, Rockie Haiyao Ding, Zixuan Zhao, Clara Yieh Lin Chong, Ruochii You, Hengjia Zhou, Dong Hua Seah, Wei Qiang Leow, Hong Kit Lim, Sukanya Shyamasundar, Kanishka Fernando, Fathima Farzana Kuthubudeen, Gillian Ng, Chor Yong Tay, Narayanan Gopalakrishna Iyer, Chin‐Ann Johnny Ong, Eliza Li Shan Fong   +16 more
wiley   +1 more source

In situ hybridization using radioisotope-labeled probe for GFA-protein messenger RNA - Comparing with immunohistochemistry and northern blot hybridization.

, 1988
Kazuo Nakanishi, Masato Okuda, Takeshi Mazaki, Teruo Mukainaka, Setsuya Fujita, Tadahisa Kitamura   +5 more
openalex   +2 more sources

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Advanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen, Sen Liu, Qiang Zhang, Xuwei Hong, Junlin Lu, Xinrou Lin, Xiao Zhao, Jiajian Lai, Kaiwen Jie, Ye Li, Jianmei Zhong, Shengmeng Peng, Siting Chen, Changhao Chen, Wenlong Zhong, Shaoxu Wu, Yihang Pan, Tianxin Lin, Xu Chen   +22 more
wiley   +1 more source

Immunohistochemistry of the Progressive and Regressive Stages of Bovine Papillomatosis [PDF]

, 1997
O. Emhmad Abdouslam, M. Levkut, M. Levkutová, Viera Révajová, R. Ondrejka, Z. Beníšek   +5 more
openalex   +1 more source

Artesunate Nanoplatform Targets the Serine–MAPK Axis in Cancer‐Associated Fibroblasts to Reverse Photothermal Resistance in Triple‐Negative Breast Cancer

Advanced Materials, EarlyView.
The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng, Jiaqi Yan, Xuejiao Liu, Zhiming Zhang, Anqi Jin, Yue Zhao, Lu Bai, Mengyao Quan, Xiuzhu Qi, Bin Fu, Zhigang Wu, Jin Zhou, Han Han, Ziqi Wang, Shiyu Wang, Chaoqiang Deng, Weijian Sun, Cai Chang, Shichong Zhou, Hongbo Zhang   +19 more
wiley   +1 more source

A Case of Paratesticular Cellular Angiofibroma Presenting as Inguinoscrotal Hernia. [PDF]

Clin Case Rep
Arif H, Faheem MSB, Memon ML, Shaheryar K, Monawwer SA, Samadi S.   +5 more
europepmc   +1 more source

Correlation of fixation, HCL hydrolysis and proteolytic digestion in bromodeoxyuridine immunohistochemistry of human stomach labeled by extracorporial perfusion system.

, 1990
Yohei Hosokawa, Yasunari Tsuchihashi, Shoji Mitsufuji, Kazuhiko Tokita, Kazushi Isetani, Toshio Tani, Tsukasa Ashihara   +6 more
openalex   +2 more sources

Interneurons of the ganglionic layer in the mormyrid electrosensory lateral line lobe: Morphology, immunohistochemistry, and synaptology [PDF]

, 1996
J. Meek, Kirsty Grant, Yoshiko Sugawara, Theo Hafmans, Michèle Veron, Jérémy Denizot   +5 more
openalex   +1 more source