Results 181 to 190 of about 1,228,272 (336)

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

Advanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen, Yingjie Fan, Tomas Germanas, Langston Tillman, Jinhong Li, Abigail L. Blenko, Ralph R. Weichselbaum, Wenbin Lin   +7 more
wiley   +1 more source

Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions

American Journal of Surgical Pathology, 2017
J. Hechtman, R. Benayed, D. Hyman, A. Drilon, A. Zehir, D. Frosina, M. Arcila, S. Dogan, D. Klimstra, M. Ladanyi, A. Jungbluth   +10 more
semanticscholar   +1 more source

Diagnostic Performance of ChatGPT-4.0 in Histopathological Analysis of Gliomas: A Single Institution Experience. [PDF]

Neuropathology
Mazzucchelli M, Salzano S, Caltabiano R, Magro G, Certo F, Barbagallo G, Broggi G.   +6 more
europepmc   +1 more source

Selective Lipolysis by Photoactivation of Chaperone‐Mediated Autophagy Using Adipocyte Membrane‐Coated Nanoparticle in Hydrogel

Advanced Materials, EarlyView.
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi, Junho Byun, Dongyoon Kim, Qiaoyun Li, Dongun Jin, Yeong‐jin Choi, Ho Sang Jung, Jaiwoo Lee, Yu‐Kyoung Oh   +8 more
wiley   +1 more source

Application of Immunohistochemistry for Diagnosis of Neoplasms: Mucin Antigens Expression and Biological Behavior of Neoplasms.

, 1994
Suguru Yonezawa
openalex   +2 more sources

Interneurons of the ganglionic layer in the mormyrid electrosensory lateral line lobe: Morphology, immunohistochemistry, and synaptology [PDF]

, 1996
J. Meek, Kirsty Grant, Yoshiko Sugawara, Theo Hafmans, Michèle Veron, Jérémy Denizot   +5 more
openalex   +1 more source

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Advanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen, Sen Liu, Qiang Zhang, Xuwei Hong, Junlin Lu, Xinrou Lin, Xiao Zhao, Jiajian Lai, Kaiwen Jie, Ye Li, Jianmei Zhong, Shengmeng Peng, Siting Chen, Changhao Chen, Wenlong Zhong, Shaoxu Wu, Yihang Pan, Tianxin Lin, Xu Chen   +22 more
wiley   +1 more source

Correlation of fixation, HCL hydrolysis and proteolytic digestion in bromodeoxyuridine immunohistochemistry of human stomach labeled by extracorporial perfusion system.

, 1990
Yohei Hosokawa, Yasunari Tsuchihashi, Shoji Mitsufuji, Kazuhiko Tokita, Kazushi Isetani, Toshio Tani, Tsukasa Ashihara   +6 more
openalex   +2 more sources

Changes in synaptic expression of clathrin assembly protein AP180 in Alzheimer's disease analysed by immunohistochemistry [PDF]

, 1999
Pamela J. Yao, Renee Morsch, Linda M. Callahan, Paul D. Coleman   +3 more
openalex   +1 more source

An Introduction to the Performance of Immunohistochemistry.

Methods in molecular biology, 2018
Shino D. Magaki, S. A. Hojat, Bowen Wei, Alexandra So, W. Yong   +4 more
semanticscholar   +1 more source