Results 231 to 240 of about 1,228,272 (336)

XBP1s Mediates Cross‐resistance to Combination Treatment of CDK4/6 Inhibitors plus Endocrine Therapy in Breast Cancer

Advanced Science, EarlyView.
Elevated spliced form of X‐box–binding protein 1 (XBP1) correlates with unfavorable responses to endocrine therapy plus CDK4/6 inhibitors in HR+/HER2− advanced breast cancer. XBP1s facilitates cell proliferation and G1/S transition by transcriptionally activating SND1, thereby activating the E2F1 pathway.
Yuting Sang, Shiyang Liu, Xujie Zhou, Weiru Chi, Min Xiong, Ming Chen, Hengyu Ren, Douwaner Liu, Liyi Zhang, Jingyan Xue, Yayun Chi, Jiong Wu   +11 more
wiley   +1 more source

Epithelioid Leiomyoma of the Uterus: A Rare Tumor Mimicking Malignancy. [PDF]

Cureus
Prabhat P, Kotian S, Kaushik N, Sharma A.   +3 more
europepmc   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source

The prognostic value of CEA, βHCG, AFP, CA125, CA19-9 and C-erb B-2, (βHCG immunohistochemistry in advanced colorectal cancer

, 1995
Aimee L. Webb, P. Scott-Mackie, David Cunningham, A. Norman, Jervoise Andreyev, Mary O’Brien, John Bensted   +6 more
openalex   +1 more source

Isolated Axillary Lymphadenopathy Presenting as Carcinoma of Unknown Primary in a Female Patient: A Diagnostic and Therapeutic Challenge. [PDF]

Cureus
M C, Bandegudda S, S S.
europepmc   +1 more source

Branched‐Chain α Keto‐Acid Dehydrogenase Kinase‐Mediated AKT Phosphorylation Promotes RCC Tumorigenesis and Drug Resistance

Advanced Science, EarlyView.
This study identifies a novel oncogenic role and a previously unrecognized phosphorylation substrate of BCKDK in RCC, wherein it promotes tumor progression and drug resistance through AKT phosphorylation at both Thr308 and Ser473 sites and activation of AKT/mTOR and AKT/ABCB1 signaling pathways, offering a promising prognostic marker and therapeutic ...
Qin Tian, Jinxiang Wang, Qiji Li, Yangruiyu Liu, Yanping Chen, Jiacheng Feng, Zi‐Ning Lei, Harsh Patel, Chao‐Yun Cai, Yuzhi Xu, Chuntao Quan, Lingyan Fei, Zexiu Xiao, Shuo Fang, Tianxin Lin, Zhe‐Sheng Chen, Yuchen Liu, Leli Zeng, Yihang Pan   +18 more
wiley   +1 more source

The histology and immunohistochemistry of free buccal mucosa and full‐skin grafts after exposure to urine

, 1999
D. Filipas, Margit Fisch, Jan Fichtner, Patricia Fitzpatrick, Kyra B. Berg, Stephan Störkel, R. Hohenfellner, J.W. Thüroff   +7 more
openalex   +1 more source

A Case of Paratesticular Cellular Angiofibroma Presenting as Inguinoscrotal Hernia. [PDF]

Clin Case Rep
Arif H, Faheem MSB, Memon ML, Shaheryar K, Monawwer SA, Samadi S.   +5 more
europepmc   +1 more source

Brain‐Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety‐Like Behaviors in Mice

Advanced Science, EarlyView.
J.Liu et al. reveal the complete propagation dynamics of cortical traveling waves, from local circuitry initiation to long‐range propagation, and identify their functional relevance in modulating anxiety‐like behaviors and underlying cellular neuroplasticity in mice.
Jiaming Liu, Jia‐Wen Mo, Xunda Wang, Yinuo Ma, Shile Tian, Qi Wang, Peng‐Li Kong, Ziqi An, Li Ding, Jing Ren, Cheng‐Lin Lu, Chuanjun Tong, Ed X. Wu, Qiu‐gen Hu, Xiong Cao, Yanqiu Feng   +15 more
wiley   +1 more source

Harmonized PD-L1 immunohistochemistry for pulmonary squamous-cell and adenocarcinomas

Modern Pathology, 2016
A. Scheel, M. Dietel, L. Heukamp, K. Jöhrens, T. Kirchner, S. Reu, J. Rüschoff, H. Schildhaus, P. Schirmacher, M. Tiemann, A. Warth, W. Weichert, R. Fischer, J. Wolf, R. Buettner   +14 more
semanticscholar   +1 more source