Results 251 to 260 of about 1,228,272 (336)

An Elderly Man with a Solitary Hypopigmented Annular Plaque on the Chest: A Quiz. [PDF]

Acta Derm Venereol
Xu J, Hu W.
europepmc   +1 more source

UCP2 Upregulates ACSL3 to Enhance Lipid Droplet Release from Acinar Cells and Modulates the Sirt1/Smad3 Pathway to Promote Macrophage‐to‐Myofibroblast Transition in Chronic Pancreatitis

Advanced Science, EarlyView.
These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang, Lilong Zhang, Beiying Deng, Wanrong Jiang, Tianrui Kuang, Chen Chen, Kailiang Zhao, Qiao Shi, Jun He, Weixing Wang   +9 more
wiley   +1 more source

MyoVision: software for automated high-content analysis of skeletal muscle immunohistochemistry.

Journal of applied physiology, 2018
Yuan Wen, Kevin A. Murach, Ivan J. Vechetti, C. Fry, Chase Vickery, C. Peterson, J. McCarthy, K. Campbell   +7 more
semanticscholar   +1 more source

Incidental primary renal extraosseous osteosarcoma: A case report. [PDF]

Int J Surg Case Rep
Do AT, Huynh DKN, Hoang NTB, Le Phan ND, Nguyen NT.   +4 more
europepmc   +1 more source

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

Advanced Science, EarlyView.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang, Xiangyu Mu, Kun Chen, Xinwen Wang, Yuluo Rong, Jia Wang, Zongcheng Yang, Chi Yin, Yuhu Dai, Jun Xiao, Wenzhi Zhang   +10 more
wiley   +1 more source

Tumor Cell Counting Using an Image Analysis Program for MIB-1 Immunohistochemistry

, 1997
Mitsunobu Ide, Minoru Jimbo, Masaaki Yamamoto, Osami Kubo   +3 more
openalex   +2 more sources

Ewing Sarcoma of the Kidney, a Rare Entity: Case Report. [PDF]

Case Rep Med
Baral A, Pun CB, Goyal B, Lamichhane S.
europepmc   +1 more source

The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer

Advanced Science, EarlyView.
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang, Bo Cheng, Chenyue Zhang, Chenglong Zhao, Ruiqing Wang, Xun Zhang, Dizhi Jiang, Xinyu Zhang, Xinyue Ma, Hongyuan Mao, Zerun Li, Chenhan Huang, Tianzi Wang, Kaiyue Guo, Liwen Wang, Ning Tang, Haiyong Wang   +16 more
wiley   +1 more source