By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley +1 more source
Long-term remission of microsatellite instability-high adenosquamous carcinoma in gastric antrum: a case report. [PDF]
Zhang P+6 more
europepmc +1 more source
AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu+8 more
wiley +1 more source
Assessment of Human Epididymis Protein 4 Expression in Breast Ductal Carcinoma In Situ. [PDF]
Kim NI, Park MH, Lee JS.
europepmc +1 more source
Prevalence of FoxP3+ Cells in Canine Tumours and Lymph Nodes Correlates Positively with Glucose Transporter 1 Expression [PDF]
A. Hibbert+67 more
core +2 more sources
Utility of immunohistochemistry in the evaluation of necrotic thyroid tumors
Alexander R. Judkins+2 more
openalex +1 more source
Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao+15 more
wiley +1 more source
OCT 4 immunohistochemistry in postpubertal cryptorchidism
Krhen Ivan+5 more
doaj +1 more source
Diagnosis of Benign and Malignant Newly Developed Nodules on the Surgical Side After Breast Cancer Surgery Based on Machine Learning. [PDF]
Wang Z+5 more
europepmc +1 more source