Results 341 to 350 of about 1,221,475 (381)

Fibroblast Activation Protein Acts as a Biomarker for Monitoring ECM Remodeling During Aortic Aneurysm via 68Ga‐FAPI‐04 PET Imaging

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
[68Ga]‐FAPI‐04 PET imaging technique represents a potential method to assess the extent of AA remodeling in vivo and may help to identify candidates at potential risk for rapid AA progression. Abstract Traditional imaging modalities used to monitor the diameter of aortic aneurysms (AAs) often fail to follow pathological progression.
Chengkai Hu   +16 more
wiley   +1 more source

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui   +17 more
wiley   +1 more source

Role of immunohistochemistry in lymphoma

open access: yesIndian Journal of Medical and Paediatric Oncology, 2010
Rao I
doaj  

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

open access: yesAdvanced Science, EarlyView.
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang   +4 more
wiley   +1 more source

Clear-cell carcinoma of the soft palate: a case with atypical presentation and long-term follow-up: a case report. [PDF]

open access: yesJ Med Case Rep
Qayyum SN   +7 more
europepmc   +1 more source

Mas Signaling Potentiates Neutrophil Extracellular Traps Formation Induced by Endothelial Cells Derived S1P in Mice with Acute Liver Failure

open access: yesAdvanced Science, EarlyView.
In mice challenged with lipopolysaccharide/D‐galactosamine (L/G), Mas signaling increased SHP2 in hepatic Col4a1+ endothelial cells, inhibiting farnesoid X receptor (FXR), potentially due to enterogenic deoxycholic acid. This inhibition activates sphingosine‐1‐phosphate‐induced Raf/MEK/ERK signaling in Cldn1+CD177+ neutrophils, causing neutrophil ...
Bo Yang   +11 more
wiley   +1 more source

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