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Integrative Computational Immunology Applied to Identify and Characterize CD8+ T-cell Neoepitopes of Shared KRAS Neoantigen Oncogenic Driver Hotspot Mutations. [PDF]
Ong LRH.
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Development and validation of novel diagnostic recombinant surface antigen D5 and cytotoxic gene pathogenesis island Cag11 protein for Helicobacter pylori. [PDF]
Eskeziyaw BM +8 more
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Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori.
Nahian M +11 more
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Immunoinformatics and Epitope Prediction
2020With advancements in sequencing technologies, vast amount of experimental data has accumulated. Due to rapid progress in the development of bioinformatics tools and the accumulation of data, immunoinformatics or computational immunology emerged as a special branch of bioinformatics which utilizes bioinformatics approaches for understanding and ...
Jayashree, Ramana, Kusum, Mehla
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Vaccines and Immunoinformatics for Vaccine Design
2022The host immune system recognizes and responds to the selective antigens or epitopes (immunome) of the intruding pathogen over an entire organism. The immune response so generated is ample to confer the desired immunity and protection to the host. This led to the conception of immunome-derived vaccines that exploit selective genome-derived antigens or ...
Shikha, Joon +2 more
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The immunoinformatics of cancer immunotherapy
Tissue Antigens, 2007AbstractWe review here the developments in the field of immunoinformatics and their present and potential applications to the immunotherapeutic treatment of cancer. Antigen presentation plays a central role in the immune response, and as a result in immunotherapeutic methods such as adoptive T‐cell transfer and antitumor vaccination.
D S, Deluca, R, Blasczyk
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Vaccine Design and Immunoinformatics
2021The emanation use of vaccines has shown tremendous applications of computational algorithms that can be used for amelioration of health globally. Vaccine Research has become a center area of research that embarks its applications to save several lives, reduced cost of treatment, and potential inhibitor of infectious diseases.
Fariya Khan, Ajay Kumar
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Immunoinformatic Identification of Potential Epitopes
2020Immunoinformatic plays a pivotal role in vaccine design and development. While traditional methods are exclusively depended on immunological experiments, they are less effective, relatively expensive, and time-consuming. However, recent advances in the field of immunoinformatics have provided innovative tools for the rational design of vaccine ...
Priti, Desai +3 more
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FROM IMMUNOINFORMATICS TO IMMUNOMICS
Journal of Bioinformatics and Computational Biology, 2003The immune system comprises a complex network of organs, specialized tissues, cells, and molecules. Its main function is to protect the organism from external and internal challenges and provides the interface between the organism and its environment. Foreign agents such as viruses, bacteria, fungi, or parasites may cause infection and disease. Foreign
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Immunoinformatics: A Brief Review
2014A large volume of data relevant to immunology research has accumulated due to sequencing of genomes of the human and other model organisms. At the same time, huge amounts of clinical and epidemiologic data are being deposited in various scientific literature and clinical records.
Namrata, Tomar, Rajat K, De
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