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Immunoinformatics Vaccine Design for Zika Virus
2023Zika virus (ZIKV) is an emerging virus from the Flaviviridae family and Flavivirus genus that has caused important outbreaks around the world. ZIKV infection is associated with severe neuropathology in newborns and adults. Until now, there is no licensed vaccine available for ZIKV infection.
Ana Clara, Antonelli +2 more
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Immunoinformatics, Molecular Modeling, and Cancer Vaccines
2014Cancer vaccines are a natural way of fighting the development and progression of cancer as they harness the power of immune system to tweak it into killing cancerous cells. One of the most important agents in an immune system, the cytotoxic T cells (CTL), play a major role and the CTL epitopes in the form of an immunotherapeutic product have been shown
Seema, Mishra, Subrata, Sinha
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Hybrid Neural Networks for Immunoinformatics
International Conference on Computational Intelligence for Modelling, Control and Automation and International Conference on Intelligent Agents, Web Technologies and Internet Commerce (CIMCA-IAWTIC'06), 2006Hybrid set of optimally trained feed-forward, Hop-field and Elman neural networks were used as computational tools and were applied to immunoinformatics. These neural networks enabled a better understanding of the functions and key components of the adaptive immune system.
K.B. Solano, T. Djekovic, M. Zohdy
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Putting immunoinformatics to the test
Nature Biotechnology, 2006A consensus epitope prediction approach identifies the epitopes responsible for 95% of the murine T-cell response to vaccinia virus.
Leonard Moise, Anne S De Groot
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Immunoinformatics: Where Immunology Meets Bioinformatics
Journal of Immunology and Immunopathology, 2019One of the most challenging research areas in biology is to understand the complex immune system and the computational tools have played a pivotal role in increasing the pace of research in the field of immunology. Thus, applications of computational methods and tools in unravelling the complex immune system and thereof translating the understanding in
Naveen Kumar +4 more
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Immunoinformatics and Systems Biology in Personalized Medicine
2014Every year new databases and tools for the storage and analysis of biological data are developed, updated, and discontinued. For this reason it is very important to have a clear picture of the major repositories providing information about the availability of these databases and tools as well as a brief description of them.
Guillermo, Lopez-Campos +3 more
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Immunoinformatics in personalized medicine.
Novartis Foundation symposium, 2004Diagnosis of human disease has been undergoing steady improvement over the past few centuries. Many ailments that were once considered a single entity have been classified into finer categories on the basis of response to therapy (e.g. type I and type II diabetes), inheritance (e.g. familial and non-familial polyposis coli), histology (e.g.
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