Results 111 to 120 of about 7,125 (263)

Interpretable deep learning to uncover the molecular binding patterns determining TCR–epitope interaction predictions

ImmunoInformatics, 2023
The recognition of an epitope by a T-cell receptor (TCR) is crucial for eliminating pathogens and establishing immunological memory. Prediction of the binding of any TCR–epitope pair is still a challenging task, especially for novel epitopes, because the
Ceder Dens, Wout Bittremieux, Fabio Affaticati, Kris Laukens, Pieter Meysman   +4 more
doaj  

AnalyzAIRR: A user-friendly guided workflow for AIRR data analysis

ImmunoInformatics
The analysis of bulk adaptive immune receptor repertoires (AIRR) enables the understanding of immune responses in both normal and pathological conditions.
Vanessa Mhanna, Gabriel Pires, Grégoire Bohl-Viallefond, Karim El Soufi, Nicolas Tchitchek, David Klatzmann, Adrien Six, Hang P. Pham, Encarnita Mariotti-Ferrandiz   +8 more
doaj  

Computational modelling of immunological mechanisms: From statistical approaches to interpretable machine learning

ImmunoInformatics, 2023
The immune system is highly complex, and its malfunctioning can result in many complex disorders. Understanding its inner workings is crucial to designing optimal immunotherapies, developing new vaccines, or understanding autoimmune diseases, just to ...
María Rodríguez Martínez, Matteo Barberis, Anna Niarakis   +2 more
doaj  

Comparison of different substitution matrices for distance based T-cell receptor epitope predictions using tcrdist3

ImmunoInformatics
Various methods, differing in complexity, have been developed to predict T-cell receptor epitopes. tcrdist3, which implements an easy-to-interpret distance-based approach, has demonstrated performance comparable to the best feature-based methods. Here, a
Marc Hoffstedt, Hermann Wätzig, Knut Baumann   +2 more
doaj  

B and T-cell Epitopes Based Vaccine Design in Api m3 Allergen of Apis mellifera: An Immunoinformatics Approach [PDF]

, 2017
Nayem Zobayer, Abul Bashar Mohammad Hossain   +1 more
openalex   +1 more source

Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools [PDF]

, 2020
Anne S. De Groot, Leonard Moise, Frances Terry, Andrés H. Gutiérrez, Pooja Hindocha, Guilhem Richard, Daniel F. Hoft, Ted M. Ross, Amy R. Noe, Yoshimasa Takahashi, Vinayaka Kotraiah, Sarah E. Silk, Carolyn M. Nielsen, Angela M. Minassian, Rebecca Ashfield, Matt Ardito, Simon J. Draper, William Martin   +17 more
openalex   +1 more source

Immunoinformatics Approach for Epitope-Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus [PDF]

, 2018
Utpal Kumar Adhikari, Mourad Tayebi, Mizanur Rahman   +2 more
openalex   +1 more source

immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking [PDF]

, 2020
Cédric R. Weber, Rahmad Akbar, Alexander Yermanos, Milena Pavlović, Igor Snapkov, Geir Kjetil Sandve, Sai T. Reddy, Victor Greiff   +7 more
openalex   +1 more source

Designing B‐ and T‐cell multi‐epitope based subunit vaccine using immunoinformatics approach to control Zika virus infection [PDF]

, 2018
Rajan Kumar Pandey, Rupal Ojha, Amit Mishra, Vijay Kumar Prajapati   +3 more
openalex   +1 more source

Synthetic Peptides Selected by Immunoinformatics as Potential Tools for the Specific Diagnosis of Canine Visceral Leishmaniasis

Microorganisms
Diagnosing canine visceral leishmaniasis (CVL) in Brazil faces challenges due to the limitations regarding the sensitivity and specificity of the current diagnostic protocol.
G. Moreira, R. Maia, Nathália Soares, T. Ostolin, W. Coura-Vital, Rodrigo Aguiar-Soares, J. Ruiz, D. Resende, R. D. De Brito, A. Reis, B. Roatt   +10 more
semanticscholar   +1 more source