Results 111 to 120 of about 7,125 (263)

Interpretable deep learning to uncover the molecular binding patterns determining TCR–epitope interaction predictions

open access: yesImmunoInformatics, 2023
The recognition of an epitope by a T-cell receptor (TCR) is crucial for eliminating pathogens and establishing immunological memory. Prediction of the binding of any TCR–epitope pair is still a challenging task, especially for novel epitopes, because the
Ceder Dens   +4 more
doaj  

AnalyzAIRR: A user-friendly guided workflow for AIRR data analysis

open access: yesImmunoInformatics
The analysis of bulk adaptive immune receptor repertoires (AIRR) enables the understanding of immune responses in both normal and pathological conditions.
Vanessa Mhanna   +8 more
doaj  

Computational modelling of immunological mechanisms: From statistical approaches to interpretable machine learning

open access: yesImmunoInformatics, 2023
The immune system is highly complex, and its malfunctioning can result in many complex disorders. Understanding its inner workings is crucial to designing optimal immunotherapies, developing new vaccines, or understanding autoimmune diseases, just to ...
María Rodríguez Martínez   +2 more
doaj  

Comparison of different substitution matrices for distance based T-cell receptor epitope predictions using tcrdist3

open access: yesImmunoInformatics
Various methods, differing in complexity, have been developed to predict T-cell receptor epitopes. tcrdist3, which implements an easy-to-interpret distance-based approach, has demonstrated performance comparable to the best feature-based methods. Here, a
Marc Hoffstedt   +2 more
doaj  

Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools [PDF]

open access: gold, 2020
Anne S. De Groot   +17 more
openalex   +1 more source

immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking [PDF]

open access: hybrid, 2020
Cédric R. Weber   +7 more
openalex   +1 more source

Synthetic Peptides Selected by Immunoinformatics as Potential Tools for the Specific Diagnosis of Canine Visceral Leishmaniasis

open access: yesMicroorganisms
Diagnosing canine visceral leishmaniasis (CVL) in Brazil faces challenges due to the limitations regarding the sensitivity and specificity of the current diagnostic protocol.
G. Moreira   +10 more
semanticscholar   +1 more source

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