Results 101 to 110 of about 2,776 (178)

IMGT-Choreography for immunogenetics and immunoinformatics.

In silico biology, 2004
IMGT, the international ImMunoGeneTics information system (http://imgt.cines.fr), was created in 1989 at Montpellier, France. IMGT is a high quality integrated knowledge resource specialized in immunoglobulins (IG), T cell receptors (TR), major histocompatibility complex (MHC) of human and other vertebrates, and related proteins of the immune system ...
Lefranc, Marie-Paule, Clément, Olivier, Kaas, Quentin, Duprat, Elodie, Chastellan, Patrick, Coelho, Isabelle, Combres, Kora, Ginestoux, Chantal, Giudicelli, Véronique, Chaume, Denys, Lefranc, Gérard   +10 more
openaire   +5 more sources

Transfer learning improves pMHC kinetic stability and immunogenicity predictions

ImmunoInformatics
The cellular immune response comprises several processes, with the most notable ones being the binding of the peptide to the Major Histocompability Complex (MHC), the peptide-MHC (pMHC) presentation to the surface of the cell, and the recognition of the ...
Romanos Fasoulis, Mauricio Menegatti Rigo, Dinler Amaral Antunes, Georgios Paliouras, Lydia E. Kavraki   +4 more
doaj   +1 more source

Multi Epitope Based Vaccine Design against Capnocytophaga canimorsus through Immunoinformatics Approaches

Immunoinformatics has provided an important contribution to the acceleration of vaccine research. The in silico tools developed under immunoinformatics efficiently filter candidate vaccines and select the most appropriate ones for in vitro and in vivo ...
Çavaş, Levent, Vatansever, Atakan
core   +1 more source

In silico single-cell metabolism analysis unravels a new transition stage of CD8 T cells 4 days post-infection

ImmunoInformatics
CD8 T cell proper differentiation during antiviral responses relies on metabolic adaptations. Herein, we investigated global metabolic activity in single CD8 T cells along an in vivo response by estimating metabolic fluxes from single-cell RNA-sequencing
Christophe Arpin, Franck Picard, Olivier Gandrillon   +2 more
doaj   +1 more source

Supplementary_table_1 – Supplemental material for Epitope-Based Peptide Vaccine Against Fructose-Bisphosphate Aldolase of Madurella mycetomatis Using Immunoinformatics Approaches

, 2018
Supplemental material, Supplementary_table_1 for Epitope-Based Peptide Vaccine Against Fructose-Bisphosphate Aldolase of Madurella mycetomatis Using Immunoinformatics Approaches by Arwa A Mohammed, Ayman MH ALnaby, Solima M Sabeel, Fagr M AbdElmarouf ...
Amina I Dirar (5964503), Solima M Sabeel (5964497), Ayman MH ALnaby (5964494), Fagr M AbdElmarouf (5964500), Magdi A Sabahalkhair (5964518), Arwa A Mohammed (5964491), Mohammed A Hassan (5964524), Abdelhameed M Yousif (5964512), Ayman E Abbas (5964521), Mostafa M Ali (5964506), Mustafa A Khandgawi (5964509), Eman M Abdulgadir (5964515)   +11 more
core   +1 more source

Is the vaccination-induced B cell receptor repertoire predictable?

ImmunoInformatics
Vaccines trigger an immune response that results in a population of memory cells that can quickly respond to subsequent antigen re-encounters. Most vaccines are designed to induce memory B cells with vaccine-specific B cell receptors (BCRs).
Eve Richardson, Lisa Willemsen, Pramod Shinde, Morten Nielsen, Bjoern Peters   +4 more
doaj   +1 more source

Construction of an immunoinformatics-based multi-epitope vaccine candidate targeting Kyasanur forest disease virus [PDF]

Kyasanur forest disease (KFD) is one of the neglected tick-borne viral zoonoses. KFD virus (KFDV) was initially considered endemic to the Western Ghats region of Karnataka state in India.
Savita Yadav, Triparna Majumdar, Yash Joshi, Sunitha Manjari Kasibhatla, Pragya Yadav, Lekshmi Rajan, Rima Sahay, Deepak Y. Patil, Anita Shete, Rajendra Joshi, Uddhavesh Sonavane, Sreelekshmy Mohandas, Vinod Jani   +12 more
core   +1 more source

Challenges for the immunoglobulin and T cell receptor gene nomenclatures in the modern genomics era

ImmunoInformatics
For over thirty years, an approach to the nomenclatures of human immunoglobulin (IG) and T cell receptor (TR) genes has operated successfully and has been widely supported by the research community. The principles behind the human nomenclatures were then
Andrew M. Collins, Corey T. Watson, Henk-Jan van den Ham, Luc Teyton, Elisa Rosati, Yana Safonova   +5 more
doaj   +1 more source

Structural insights on the differentiation and reversion of conformational changes in SARS-CoV-2 spike protein models across variants occurring from December, 2019 to November, 2021

ImmunoInformatics
Conformational changes in the SARS-CoV-2 spike protein are critical for understanding viral evolution. In this study, we provide comparative structural and electrostatic analyses across variants, revealing both differentiation and reversion patterns not ...
Marni E. Cueno, Kenichi Imai
doaj   +1 more source

Building immunoglobulin and T cell receptor gene databases for the future

ImmunoInformatics
Genetic databases for immunoglobulin (IG) and T cell receptor (TR) genes have evolved from small catalogs to critical resources underpinning immunogenetic research.
Corey T. Watson, Andrew M. Collins, Mats Ohlin, James M. Heather, Ayelet Peres, William D. Lees, Gur Yaari   +6 more
doaj   +1 more source