Results 81 to 90 of about 7,150 (221)

Analysis of vitellogenin gene structure in Caspian roach, Rutilus caspicus (Pisces: Cyprinidae) during exposure to Atrazine [PDF]

, 2017
Chemical contamination of aquatic environments to EDCs has become a major focus of environmental toxicology research. The exposure of fishes to estrogenic EDCs in aquatic environments is most frequently assessed by analyzing Vitellogenin (Vg) (the egg ...
Behdani, M., Jamili, Sh., Mashinchian Moradi, A., Oveysi, M., Sharifpoor, E.   +4 more
core  

Mutanome and expression of immune response genes in microsatellite stable colon cancer [PDF]

, 2017
The aim of this study was to analyze the impact of the mutanome in the prognosis of microsatellite stable stage II CRC tumors. The exome of 42 stage II, microsatellite stable, colon tumors (21 of them relapse) and their paired mucosa were sequenced and ...
Alemany Bonastre, Ramon, Alonso Aguado, Maria Henar, Aussó, Susanna, Garcia i Molleví, David, Gil Hoyos, Raúl, López Dóriga Guerra, Adriana, Moreno Aguado, Víctor, Salazar Soler, Ramón, Sanjuan, Xavier, Santos, Cristina, Sanz Pamplona, Rebeca   +10 more
core   +1 more source

Role of NTRK Fusion Genes in the Tumor Immune Microenvironment of HPV (+/−) Cervical Cancer

Journal of Medical Virology, Volume 97, Issue 8, August 2025.
ABSTRACT Cervical cancer, a prevalent gynecological malignancy, is primarily associated with human papillomavirus (HPV) infection. However, some cases display distinct molecular alterations beyond HPV, significantly impacting the tumor immune microenvironment (TIME) and posing therapeutic challenges.
Qiongying Wang, Chan Zhang, Shijia Liu, Wangshu Li, Wenjuan Wei, Aziz ur Rehman Aziz, Han Lu, Daqing Wang   +7 more
wiley   +1 more source

Kemokinek, kemokin receptorok expressziójának regulációja tumor sejteken = Regulation of chemokine and chemokine receptor expression in tumor cells [PDF]

, 2008
A tumor és mikrokörnyezete közötti kapcsolatban a kemokineknek és a tumor sejteken található kemokin receptoroknak mind nagyobb jelentőséget tulajdonítanak.
Balázs, Annamária, Pócsik, Éva, Szentes, Tamás   +2 more
core  

Mycobacterium tuberculosis Complex Exhibits Lineage-Specific Variations Affecting Protein Ductility and Epitope Recognition [PDF]

, 2016
The advent of whole-genome sequencing has provided an unprecedented detail about the evolution and genetic significance of species-specific variations across the whole Mycobacterium tuberculosis Complex.
Contreras-Moreira, Bruno, Gonzalo-Asensio, Jesús, Magalhães, Carlos André Rodrigues, Osório, Nuno S., Yruela, Inmaculada   +4 more
core   +2 more sources

TRain: T-cell receptor automated immunoinformatics

BMC Bioinformatics
The scarcity of available structural data makes characterizing the binding of T-cell receptors (TCRs) to peptide-Major Histocompatibility Complexes (pMHCs) very challenging. The recent surge in sequencing data makes TCRs an ideal target for protein structure modeling. Through these 3D models, researchers can potentially identify key motifs on the TCR's
Austin Seamann, Maia Bennett-Boehm, Ryan Ehrlich, Anna Gil, Liisa Selin, Dario Ghersi   +5 more
openaire   +3 more sources

Navigating the immunosuppressive brain tumor microenvironment using spatial biology

ImmunoInformatics
With the application of spatial biology, the detection and identification of the diverse cell types present in the tumor microenvironment, including specific immune subsets, is possible at single cell resolution.
Samuel S. Widodo, Marija Dinevska, Stanley S. Stylli, Adriano L. Martinelli, Marianna Rapsomaniki, Theo Mantamadiotis   +5 more
doaj   +1 more source

Transfer learning improves pMHC kinetic stability and immunogenicity predictions

ImmunoInformatics
The cellular immune response comprises several processes, with the most notable ones being the binding of the peptide to the Major Histocompability Complex (MHC), the peptide-MHC (pMHC) presentation to the surface of the cell, and the recognition of the ...
Romanos Fasoulis, Mauricio Menegatti Rigo, Dinler Amaral Antunes, Georgios Paliouras, Lydia E. Kavraki   +4 more
doaj   +1 more source

In silico single-cell metabolism analysis unravels a new transition stage of CD8 T cells 4 days post-infection

ImmunoInformatics
CD8 T cell proper differentiation during antiviral responses relies on metabolic adaptations. Herein, we investigated global metabolic activity in single CD8 T cells along an in vivo response by estimating metabolic fluxes from single-cell RNA-sequencing
Christophe Arpin, Franck Picard, Olivier Gandrillon   +2 more
doaj   +1 more source

Characterizing the normal proteome of human ciliary body [PDF]

, 2013
BACKGROUND: The ciliary body is the circumferential muscular tissue located just behind the iris in the anterior chamber of the eye. It plays a pivotal role in the production of aqueous humor, maintenance of the lens zonules and accommodation by changing
Akhilesh Pandey, Anil K Madugundu, Dhanashree S Kelkar, Gourav Dey, HC Harsha, Krishna R Murthy, Mitali Bhattacharjee, Renu Goel, Shukti Chakravarti, Sneha M Pinto, Srinivas M Srikanth, Sujatha S Mohan, TS Prasad, Venkatarangaiah Krishna   +13 more
core   +1 more source