Results 81 to 90 of about 2,776 (178)

FungalRV: adhesin prediction and immunoinformatics portal for human fungal pathogens [PDF]

, 2011
Background The availability of sequence data of human pathogenic fungi generates opportunities to develop Bioinformatics tools and resources for vaccine development towards benefitting at-risk patients.
Ansari Faraz, Raghunandanan Muthukurussi, Rupanjali Chaudhuri, Faraz Alam Ansari, Ramachandran Srinivasan, Muthukurussi Varieth Raghunandanan, Chaudhuri Rupanjali, Srinivasan Ramachandran   +7 more
core   +2 more sources

Utility of immunoinformatics in epitope mapping for vaccine and therapeutic design

Epitope identification is largely the basis for the development of new vaccine candidates and immunotherapies. However, traditional methods for epitope identification present certain limitations in terms of time and high costs, hence experimentation in ...
Vitón Castillo, Adrián Alejandro, Miló Valdés, Carlos Alfredo, Pérez Acevedo, Lidia Cecilia   +2 more
core   +2 more sources

Hybrid neural networks for immunoinformatics

, 2005
Hybrid set of optimally trained feed-forward, Hop-field and Elman neural networks were used as computational tools and were applied to immunoinformatics.
Solano, Khrizel B., Zohdy, Mohamed, Djekovic, Tolja   +2 more
core   +1 more source

Deep Learning‐Enabled Engineering of a Hyper‐Stable and Soluble MPB70‐83 Antigen for Sensitive Bovine Tuberculosis Surveillance

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
Schematic representation of the research workflow for the efficient diagnosis of bovine tuberculosis employing peptide fusion proteins. ABSTRACT Bovine tuberculosis (bTB) diagnostics are frequently hindered by the structural instability and insolubility of recombinant multi‐epitope proteins in prokaryotic expression systems.
Wen‐Hao Wang, Jia‐Zhen Ge, Ying‐Ying Xie, Guo‐Dong Song, Yijian Liu, Yin‐juan Song, Ren‐ge Li, Rui‐Shuang Li, Zi‐qing Wang, Xin‐Miao Liu, Shuang‐Shuang Guo, Jie Li, Shengli Chen, Na Li, Fuying Zheng, Yuefeng Chu   +15 more
wiley   +1 more source

IMGT-Choreography for immunogenetics and immunoinformatics.

, 2005
International audienceIMGT, the international ImMunoGeneTics information system (http://imgt.cines.fr), was created in 1989 at Montpellier, France. IMGT is a high quality integrated knowledge resource specialized in immunoglobulins (IG), T cell receptors
Combres, Kora, Chaume, Denys, Kaas, Quentin, Duprat, Elodie, Lefranc, Gérard, Ginestoux, Chantal, Chastellan, Patrick, Giudicelli, Véronique, Lefranc, Marie-Paule, Clément, Olivier, Coelho, Isabelle   +10 more
core   +1 more source

Where single-cell transcriptomics fails T cells: The misuse of unsupervised clustering for T-cell annotationThis perspective used publicly available data (DOI: 10.5281/zenodo.12569981; ).

ImmunoInformatics
The current state of single-cell transcriptomic interrogation typically consists of using an unsupervised clustering approach followed by expert opinion-based annotation.
Kerry A. Mullan, Sebastiaan Valkiers, Nicky de Vrij, Chen Li, Sara Verbandt, Ting Pu, Pieter Meysman   +6 more
doaj   +1 more source

The emerging potential of immunoinformatics prediction tools

, 2009
The emerging potential of immunoinformatics prediction ...
J Orbell (13299585), S Chandler (12300140), S Khetarpad (13737658), Morley Muralitharan (13085757)   +3 more
core  

Search continues: Exploring immunoinformatics platforms for designing an effective multiepitope malaria vaccine candidate

Background The prevailing public health threat posed by malaria, especially in developing countries, remains a serious concern despite the availability of preventive and control measures. While vaccination offers a powerful means of combating malaria, it
Charles Osuji, Godwin Etuk-Udo
core   +1 more source

Comparison of different substitution matrices for distance based T-cell receptor epitope predictions using tcrdist3

ImmunoInformatics
Various methods, differing in complexity, have been developed to predict T-cell receptor epitopes. tcrdist3, which implements an easy-to-interpret distance-based approach, has demonstrated performance comparable to the best feature-based methods. Here, a
Marc Hoffstedt, Hermann Wätzig, Knut Baumann   +2 more
doaj   +1 more source

AnalyzAIRR: A user-friendly guided workflow for AIRR data analysis

ImmunoInformatics
The analysis of bulk adaptive immune receptor repertoires (AIRR) enables the understanding of immune responses in both normal and pathological conditions.
Vanessa Mhanna, Gabriel Pires, Grégoire Bohl-Viallefond, Karim El Soufi, Nicolas Tchitchek, David Klatzmann, Adrien Six, Hang P. Pham, Encarnita Mariotti-Ferrandiz   +8 more
doaj   +1 more source