Machine learning in AIRR diagnostics: Advances and applications
Recent advancements in sequencing technologies have led to an exponential increase in adaptive immune receptor repertoire (AIRR) data. These receptors, crucial to the adaptive immune system, are believed to have strong potential for diagnostic ...
Aslı Semerci +9 more
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Immunoinformatics: Implications on Reverse Vaccinology
One area in which immunological studies have had most immediate and successful application is in the field of vaccination. Vaccines represent one of the greatest interventions in modern medicine [1]. Ever since Edward Jenner’s first use of a vaccine against smallpox in 1796, the use of vaccines has become indispensable to the eradication of disease [2].
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Do domain-specific protein language models outperform general models on immunology-related tasks?
Deciphering the antigen recognition capabilities by T-cell and B-cell receptors (antibodies) is essential for advancing our understanding of adaptive immune system responses.
Nicolas Deutschmann +5 more
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T-cell receptor binding prediction: A machine learning revolution
Recent advancements in immune sequencing and experimental techniques are generating extensive T cell receptor (TCR) repertoire data, enabling the development of models to predict TCR binding specificity.
Anna Weber +2 more
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Editorial: Exploring immune evasion and vaccine strategies in host-pathogen interactions. [PDF]
Kumaresan V +3 more
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Preliminary Immunogenicity Evaluation of an Immunoinformatics-Guided Multi-Epitope mRNA Vaccine Against Porcine Epidemic Diarrhea Virus. [PDF]
Liu Y, Huang H, Chen Y, Shu J, Wu F.
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Correction: Immunoinformatics-driven multi-epitope vaccine design targeting PSMA, STEAP1, and B7H3 for prostate cancer. [PDF]
Runtunuwu SVBE +12 more
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From <i>in silico</i> to <i>in vitro</i>: discovery and validation of peptide modulators of IL-6/IL-6R signaling in rheumatoid arthritis. [PDF]
Yang J, Wang Y, Huang J, Zhang J, Xie Y.
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Correction: Design of a multi-epitope recombinant BCG vaccine targeting Brucella OMP31, LptE and VirB2 in immunoinformatics approaches. [PDF]
PLOS One Staff.
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