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Is the vaccination-induced B cell receptor repertoire predictable? [PDF]

open access: yesImmunoInformatics
Vaccines trigger an immune response that results in a population of memory cells that can quickly respond to subsequent antigen re-encounters. Most vaccines are designed to induce memory B cells with vaccine-specific B cell receptors (BCRs).
Eve Richardson   +4 more
doaj   +2 more sources

Unique chicken B cell development: species-specific mechanisms and contradictory requirements of B cell receptor for post-hatched B cell development [PDF]

open access: yesFrontiers in Immunology
Chicken B cell development represents a remarkable evolutionary divergence from mammalian paradigms, featuring unique three-stage ontogeny centered on the bursa of Fabricius, an avian-specific primary B cell lymphoid organ.
Seung Je Woo   +2 more
doaj   +2 more sources

T-cell receptor and B-cell receptor repertoires profiling in pleural tuberculosis [PDF]

open access: yesFrontiers in Immunology
BackgroundTuberculosis (TB) is a leading cause of death worldwide from a single infectious agent. In China the most common extra-pulmonary TB (EPTB) is pleural tuberculosis (PLTB).
Fengjiao Du   +12 more
doaj   +2 more sources

B cell receptor repertoire abnormalities in autoimmune disease [PDF]

open access: yesFrontiers in Immunology
B cells play a crucial role in the immune response and contribute to various autoimmune diseases. Recent studies have revealed abnormalities in the B cell receptor (BCR) repertoire of patients with autoimmune diseases, with distinct features observed ...
Hayato Yuuki   +7 more
doaj   +2 more sources

B cell receptor dependent enhancement of dengue virus infection. [PDF]

open access: yesPLoS Pathogens
Dengue virus (DENV) is the causative agent of dengue, a mosquito-borne disease that represents a significant and growing public health burden around the world.
Chad Gebo   +12 more
doaj   +2 more sources

Aberrant B Cell Signaling in Autoimmune Diseases

open access: yesCells, 2022
Aberrant B cell signaling plays a critical in role in various systemic and organ-specific autoimmune diseases. This is supported by genetic evidence by many functional studies in B cells from patients or specific animal models and by the observed ...
Odilia B. J. Corneth   +2 more
doaj   +1 more source

Severe acute respiratory syndrome coronavirus 2 targeted antibodies cocktail and B cell receptor interplay: interventions to trigger vaccine development

open access: yesExploration of Immunology, 2021
Coronavirus disease-2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2 spread globally and creates an alarming situation.
Kabeer Haneef   +7 more
doaj   +1 more source

The dynamics and association of B and T cell receptor repertoires upon antibody response to hepatitis B vaccination in healthy adults

open access: yesHuman Vaccines & Immunotherapeutics, 2021
The Hepatitis B (HB) vaccine is efficacious in preventing hepatitis B virus infection. However, the association between antibody response to the HB vaccine and dynamic immune repertoire changes in different cell subsets remains unclear.
Miaoxian Zhao   +8 more
doaj   +1 more source

Immunoglobulin M-degrading enzyme of Streptococcus suis (IdeSsuis) impairs porcine B cell signaling

open access: yesFrontiers in Immunology, 2023
Streptococcus suis (S. suis) is an important porcine pathogen, causing severe disease like meningitis and septicemia primarily in piglets. Previous work showed that the IgM-degrading enzyme of S.
Annika Katharina Breitfelder   +6 more
doaj   +1 more source

Regulation of cell adhesion to galectins by glycosylation: A new concept in lymphoma cell adhesion

open access: yesAdvances in Cancer Biology - Metastasis, 2021
To investigate the biological roles of glycosylation in human lymphoma cell adhesion to galectins, I performed the cell adhesion assay using neuraminidase or glycosylation inhibitors on B cell lymphoma cell line.
Osamu Suzuki
doaj   +1 more source

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