Results 11 to 20 of about 2,912,674 (304)

Regulation of cell adhesion to galectins by glycosylation: A new concept in lymphoma cell adhesion

Advances in Cancer Biology - Metastasis, 2021
To investigate the biological roles of glycosylation in human lymphoma cell adhesion to galectins, I performed the cell adhesion assay using neuraminidase or glycosylation inhibitors on B cell lymphoma cell line.
Osamu Suzuki
doaj   +1 more source

Severe acute respiratory syndrome coronavirus 2 targeted antibodies cocktail and B cell receptor interplay: interventions to trigger vaccine development

Exploration of Immunology, 2021
Coronavirus disease-2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2 spread globally and creates an alarming situation.
Kabeer Haneef, Rabia Saleem, Muhammad Saleem Iqbal Khan, Olawale Samuel Adeyinka, Sadeeq Banday, Muhammad Umer Asghar, Zia Ur Rahman, Zainab Fatima   +7 more
doaj   +1 more source

Mechanisms of B Cell Receptor Activation and Responses to B Cell Receptor Inhibitors in B Cell Malignancies [PDF]

Cancers, 2020
The B cell receptor (BCR) pathway has been identified as a potential therapeutic target in a number of common B cell malignancies, including chronic lymphocytic leukemia, diffuse large B cell lymphoma, Burkitt lymphoma, follicular lymphoma, mantle cell lymphoma, marginal zone B cell lymphoma, and Waldenstrom’s macroglobulinemia.
Dimitar G. Efremov, Sven Turkalj, Luca Laurenti   +2 more
openaire   +3 more sources

Role of an adaptor protein human germinal center-associated lymphoma (HGAL) in cell signaling and lymphomagenesis

Exploration of Immunology, 2023
Human germinal center (GC)-associated lymphoma (HGAL) is a multi-domain adaptor protein expressed in GC B lymphocytes, T follicular helper (Tfh) cells and lymphomas derived from these cells.
Xiaoyu Jiang, Izidore S. Lossos
doaj   +1 more source

B cell receptor signatures associated with strong and poor SARS-CoV-2 vaccine responses

Emerging Microbes and Infections, 2022
Breakthrough infection of SARS-CoV-2 is a serious challenge, as increased infections were documented in fully-vaccinated individuals. Recipients with poor antibody response are highly vulnerable to reinfection, whereas those with strong antibody ...
Ke Lin, Yawen Zhou, Jingwen Ai, Yan A. Wang, Senxin Zhang, Chao Qiu, Chaoyang Lian, Bo Gao, Tingting Liu, Hongyu Wang, Haocheng Zhang, Yi Zhang, Zhangfan Fu, Dan Li, Ning Jiang, Jingxin Guo, Jing Wu, Yan O. Wang, Shusen Song, Qiang Li, Yanan Yin, Jia Xia, Yingjie Xu, Leng-Siew Yeap, Xiaoqi Zheng, Ye Gu, Hongyan Liu, Wenhong Zhang, Fei-Long Meng   +28 more
doaj   +1 more source

IgD shapes the pre-immune naïve B cell compartment in humans

Frontiers in Immunology, 2023
B cell maturation and immunoglobulin (Ig) repertoire selection are governed by expression of a functional B cell receptor (BCR). Naïve B cells co-express their BCR as IgM and IgD isotype.
Johannes Dirks, Oliver Andres, Luisa Paul, Luisa Paul, Georgi Manukjan, Harald Schulze, Henner Morbach   +6 more
doaj   +1 more source

Atypical chemokine receptor 4 shapes activated B cell fate [PDF]

, 2018
Activated B cells can initially differentiate into three functionally distinct fates-early plasmablasts (PBs), germinal center (GC) B cells, or early memory B cells-by mechanisms that remain poorly understood.
Alsharifi, Mohammed, Babb, Rachelle, Bastow, Cameron R., Bourne, Katherine, Brink, Robert, Comerford, Iain, Cyster, Jason G., Fenix, Kevin A., Gilchrist, Derek S., Gregor, Carly E., Hermes, Jana R., Hill, Geoffrey R., Kara, Ervin E., McColl, Shaun R., McKenzie, Duncan R., Nibbs, Robert J., Norton, Todd S., Rodda, Lauren B., Tarlinton, David M., Vinuesa, Carola G., Zotos, Dimitra   +20 more
core   +2 more sources

Aberrant B-Cell Activation in Systemic Lupus Erythematosus

Kidney Diseases, 2022
Background: B lymphocytes (B cells) are essential in humoral response, and their activation is an important first step for the production of antibodies.
Na Kang, Xiaohang Liu, Xujie You, Wenbo Sun, Kabeer Haneef, Xiaolin Sun, Wanli Liu   +6 more
doaj   +1 more source

Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]

, 2009
Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter, Grove, Joe, Hu, Ke, McKeating, Jane A, Mee, Christopher J, Schwarz, Anne K   +5 more
core   +2 more sources

B Cell Receptor Signaling Pathway Mutation as Prognosis Predictor of Immune Checkpoint Inhibitors in Lung Adenocarcinoma by Bioinformatic Analysis

Journal of Inflammation Research, 2022
Anqi Lin,1,* Jianbo Fang,1,* Quan Cheng,2,3 Zaoqu Liu,4 Peng Luo,1 Jian Zhang1 1Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 2Department of Neurosurgery, Xiangya ...
Lin A, Fang J, Cheng Q, Liu Z, Luo P, Zhang J   +5 more
doaj