Results 111 to 120 of about 2,776 (178)

Machine learning in AIRR diagnostics: Advances and applications

open access: yesImmunoInformatics
Recent advancements in sequencing technologies have led to an exponential increase in adaptive immune receptor repertoire (AIRR) data. These receptors, crucial to the adaptive immune system, are believed to have strong potential for diagnostic ...
Aslı Semerci   +9 more
doaj   +1 more source

THE IMPORTANCE AND RELEVANCE OF IMMUNOINFORMATICS IN MODERN MEDICAL PRACTICE OF DISEASE PREVENTION AND TREATMENT

open access: yes
For a number of illnesses, such as cancer, autoimmune disorders and infectious diseases, the immune system is crucial to the creation of tailored treatment.  Computational immunology, often known as immunoinformatics, is a new field that offers ...
Khozhiev, Khumoyun
core   +1 more source

Immunoinformatics: Implications on Reverse Vaccinology

open access: yesImmunochemistry & Immunopathology, 2017
One area in which immunological studies have had most immediate and successful application is in the field of vaccination. Vaccines represent one of the greatest interventions in modern medicine [1]. Ever since Edward Jenner’s first use of a vaccine against smallpox in 1796, the use of vaccines has become indispensable to the eradication of disease [2].
openaire   +1 more source

Do domain-specific protein language models outperform general models on immunology-related tasks?

open access: yesImmunoInformatics
Deciphering the antigen recognition capabilities by T-cell and B-cell receptors (antibodies) is essential for advancing our understanding of adaptive immune system responses.
Nicolas Deutschmann   +5 more
doaj   +1 more source

Immunoinformatics Approach to T-cell Epitopes in Human Immunodeficiency Virus [PDF]

open access: yes, 2013
Human immunodeficiency virus (HIV) is major human disease which belongs to lentivirus (retrovirus). It is a major cause of acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life ...
Deval, Ravi   +7 more
core  

Structural and immunoinformatics analysis of M. tuberculosis PpiA.

open access: yes, 2014
Fig. 3A: Structural overlapping of M. tuberculosis PpiA (green) with human PPWD1 (yellow) demonstrated almost complete overlap, (inset showing the loop region). Fig. 3B: Comparative analysis of structural overlapping between M.
Abhijit Maji (519936)   +10 more
core   +1 more source

T-cell receptor binding prediction: A machine learning revolution

open access: yesImmunoInformatics
Recent advancements in immune sequencing and experimental techniques are generating extensive T cell receptor (TCR) repertoire data, enabling the development of models to predict TCR binding specificity.
Anna Weber   +2 more
doaj   +1 more source

Bioinformatics and immunoinformatics assisted multiepitope vaccine construct against Burkholderia anthina

open access: yes
Burkholderia anthina is a pathogenic bacterial species belonging to the Burkholderiaceae family and it is mainly considered the etiological agent of chronic obstructive pulmonary diseases associated with cystic fibrosis, due to being intrinsic antibiotic
Wafa Abdullah I. Al-Megrin   +10 more
core   +1 more source

Design of a novel multi epitope antigen for diagnosis of visceral leishmaniasis using an immunoinformatics approach

open access: yes
Visceral Leishmaniasis (VL) represents a critical parasitic disease with considerable implications for public health. The predominant etiological agent responsible for most VL cases in the Mediterranean region and Latin America is the Leishmania infantum
Samaneh Hashemi   +7 more
core   +1 more source

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