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Immunoinformatics Vaccine Design for Zika Virus
2023Zika virus (ZIKV) is an emerging virus from the Flaviviridae family and Flavivirus genus that has caused important outbreaks around the world. ZIKV infection is associated with severe neuropathology in newborns and adults. Until now, there is no licensed vaccine available for ZIKV infection.
Ana Clara, Antonelli +2 more
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Putting immunoinformatics to the test
Nature Biotechnology, 2006A consensus epitope prediction approach identifies the epitopes responsible for 95% of the murine T-cell response to vaccinia virus.
Leonard Moise, Anne S De Groot
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Immunoinformatics in Drug Designing
Immunoinformatics is a sub-branch of immunology that was risen from the huge amount of data generated from tons of genomic and proteomic projects dealing with the host- pathogen interactions in the need of analyzing these data. Immunoinformatics primarily focuses on predicting the algorithmic mapping of epitopes, thus reducing both cost and time ...Das, Anwesha +3 more
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Immunoinformatics, Molecular Modeling, and Cancer Vaccines
2014Cancer vaccines are a natural way of fighting the development and progression of cancer as they harness the power of immune system to tweak it into killing cancerous cells. One of the most important agents in an immune system, the cytotoxic T cells (CTL), play a major role and the CTL epitopes in the form of an immunotherapeutic product have been shown
Seema, Mishra, Subrata, Sinha
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Immunoinformatics and Systems Biology in Personalized Medicine
2014Every year new databases and tools for the storage and analysis of biological data are developed, updated, and discontinued. For this reason it is very important to have a clear picture of the major repositories providing information about the availability of these databases and tools as well as a brief description of them.
Guillermo, Lopez-Campos +3 more
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Immunoinformatics as a Tool for New Antifungal Vaccines
2017Immunoinformatics aids in screening for vaccine candidates, which can be experimentally tested for their efficacy. This chapter describes methods to use immunoinformatics to screen fungal vaccines candidates. Surface-localized molecules called adhesins could elicit immune response and serve as efficient vaccine candidates.
Rupanjali, Chaudhuri +1 more
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Immunoinformatics and the prediction of immunogenicity.
Applied bioinformatics, 2004Immunoinformatics is the application of informatics techniques to molecules of the immune system. One of the key goals of immunoinformatics is the development of computer aided vaccine design (CAVD), or computational vaccinology, and its application to the search for new vaccines.
Darren R, Flower, Irini A, Doytchinova
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State of the Art of Immunoinformatics
Vaccinology is the study of vaccines, their development, and their use. Classical vaccinology, practiced for centuries, relies on identifying and isolating a pathogen's protective antigens. Classical vaccinology has successfully developed vaccines against many diseases, including smallpox, measles, mumps, and diphtheria.Eduarda Guimarães Sousa +14 more
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