Results 161 to 170 of about 55,236 (336)

Cortical actin recovery at the immunological synapse leads to termination of lytic granule secretion in cytotoxic T lymphocytes [PDF]

, 2017
Alex T. Ritter, Senta M. Kapnick, Sricharan Murugesan, Pamela L. Schwartzberg, Gillian M. Griffiths, Jennifer Lippincott‐Schwartz   +5 more
openalex   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

Butyrate confers colorectal cancer cell resistance to anti-PD-1 therapy by promoting CPT1A-mediated fatty acid oxidation

Discover Oncology
Immunotherapy including anti-PD-1 demonstrated therapeutic promise to colorectal cancer (CRC) patients, but tumor cell resistance limits their efficacy.
Ran Zhu, Shujiang Gu, Yuan Tao, Yan Zhang   +3 more
doaj   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma

, 2022
Turan Aghayev, Aleksandra Mazitova, Jennifer R. Fang, Iuliia O. Peshkova, Matthew Rausch, Man‐Hsin Hung, Kerry White, Ricard Masia, Elizaveta K. Titerina, Aliia R. Fatkhullina, Isabelle Cousineau, Simon Turcotte, Dmitry Zhigarev, Anastasiia Marchenko, Svetlana Khoziainova, Petr Makhov, Yin Fei Tan, Andrew V. Kossenkov, David L. Wiest, John Stagg, Xin Wei Wang, Kerry S. Campbell, Amiran Dzutsev, Giorgio Trinchieri, Jonathan A. Hill, Sergei I. Grivennikov, Ekaterina K. Koltsova   +26 more
openalex   +2 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Significance of some factors in the pathogenesis of hemorrhagic fevers [PDF]

Vojnosanitetski Pregled, 2003
Bojić Ivanko, Pavlović Milorad, Pelemiš Mijomir, Đokić Milomir, Begović Vesna   +4 more
doaj   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

375 Dendritic cells co-transduced with an interleukin (IL)-12- or CD40L-expressing adenovirus and an AFP-encoding adenovirus enhance the cytotoxic activity of immunologic effector cells against AFP-expressing HCC cells

, 2006
Maria A. González-Carmona, Cindy Schneider, A. Timmerman, S Shabani, Elisabeth Sievers, Ingo G.H. Schmidt‐Wolf, Verônica Schmitz, Tilman Sauerbruch, Wolfgang H. Caselmann   +8 more
openalex   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source