Results 251 to 260 of about 55,236 (336)

Desensitization Strategies in Immunized Heart Transplant Recipients.

Eur Surg Res
Goerler A, Kruszona S, Aburahma K, de Manna ND, Salman J, Ruhparwar A, Avsar M, Schmack B, Ius F.   +8 more
europepmc   +1 more source

Engineering Innate Immunity: Recent Advances and Future Directions for CAR-NK and CAR-Macrophage Therapies in Solid Tumors. [PDF]

Cancers (Basel)
Amoozgar B, Bangolo A, Mansour C, Elias D, Mohamed A, Thor DC, Ehsanullah SU, Tran HH, Aguilar IK, Weissman S.   +9 more
europepmc   +1 more source

Cytotoxic and Immunologic Effects of Measles Oncolytic Virus on Colon Cancer Cells

Reyam Abdul Khuder Mohammed, Zaytoon Abdulrida Al-Khafaji, Kaiser N. Madlum   +2 more
openalex   +2 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

LIMD2 is associated with an exhausted CD8⁺ T cell state linked to ICI response in clear cell renal cell carcinoma. [PDF]

Sci Rep
Zhang J, Peng Q, Xiang X, Liu F, Jiang X, Nie H, Bi X, Pan T, Li K, Chen P, Yuan S, Chen S.   +11 more
europepmc   +1 more source

Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients

, 2008
F. Stephen Hodi, Marcus O. Butler, Darryl A. Oble, Michael V. Seiden, Frank G. Haluska, Andrea Kruse, Suzanne MacRae, Marybeth Nelson, Christine Canning, Israel Lowy, Alan J. Korman, David B. Lautz, Sara E. Russell, Michael T. Jaklitsch, Nikhil H. Ramaiya, Teresa C. Chen, Donna Neuberg, James P. Allison, Martín C. Mihm, Glenn Dranoff   +19 more
openalex   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Carbon dot-lipidoid nanocarriers for superiorly biocompatible nasal mRNA cancer vaccination. [PDF]

J Nanobiotechnology
Kim H, Jeong H, Kim YA, Kim KS, Yun JW, Li F, Ling D, Na K.   +7 more
europepmc   +1 more source

Differential survival of hamster-to-rat liver and cardiac xenografts under FK 506 immunosuppression [PDF]

, 1991
Demetris, AJ, Fung, JJ, Starzl, TE, Valdivia, LA   +3 more
core  

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source