Results 261 to 270 of about 55,236 (336)

Longitudinal T-Cell Phenotypic Dynamics During Sustained Antiretroviral Therapy in People With HIV. [PDF]

Open Forum Infect Dis
Vanpouille C, Wells A, DeGruttola V, Lynch M, Zhang X, Tu XM, Chaillon A, Woodworth B, Gaitan N, Rawlings SA, Landay A, Weber KM, Scully EP, Karn J, Gianella S.   +14 more
europepmc   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Long-Acting Recombinant IL-7 (rhIL-7-hyFc) Enhances the Primary and Memory Neoantigen-Specific Immune Response to Breast Cancer Personalized Cancer Vaccines. [PDF]

Cancers (Basel)
Chen M, Kane T, Chen I, Supabphol S, Zhang X, Wolfarth AA, Choi D, Li L, Goedegebuure SP, Gillanders WE.   +9 more
europepmc   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Chimeric Antigen Receptor T Cell Therapy in Systemic Lupus Erythematosus: Mechanisms, Clinical Advances, and Future Directions a Comprehensive Review. [PDF]

Clin Rev Allergy Immunol
Matarneh A, Matarneh B, Salameh O, Akkari A, Ghahramani N, Trivedi N.   +5 more
europepmc   +1 more source

Milestones in Transplantation: The Story so Far [PDF]

, 2001
Starzl, TE
core  

Novel TLR7 agonist stimulates activity of CIK/NK immunological effector cells to enhance antitumor cytotoxicity

, 2018
Dong Gao, Yongguang Cai, Yanyuan Chen, Wang Li, Chih‐Chang Wei, Xiaoling Luo, Yuhuan Wang   +6 more
openalex   +2 more sources

A Microbiota‐ and IL‐15‐Dependent Innate‐Like B Cell Progenitor Expressing E4BP4

Advanced Science, EarlyView.
This work identifies CD3.NKp46.CD19.NK1.1. NK‐B cells enriched in PDK1‐deficient yet present in wild‐type bone marrow. IL‐15 (via CD122) and TLR9‐microbiota signaling maintain their E4BP4 expression. These cells demonstrate innate immunity, preferentially differentiate into B cells, and unveil a novel microbiota‐ and IL‐15‐dependent regulatory pathway ...
Junming He, Xinlei Hou, Xiaomei Feng, Yayun Dong, Mengqi Ren, Surong Deng, Xinru Yang, Donglin Chen, Lingna Zhao, Shasha Chen, Meixiang Yang, Zhongjun Dong   +11 more
wiley   +1 more source

Quantification of timelapse 3D tumor spheroid killing activity of NK cells using a live-cell imaging system. [PDF]

PLoS One
Srisantitham J, Thongsin N, Suwanpitak S, Wattanapanitch M.   +3 more
europepmc   +1 more source