Results 271 to 280 of about 880,908 (352)

Development and Application of Organic Sonosensitizers in Cancer Therapy

Aggregate, EarlyView.
This review provides a comprehensive overview of organic sonosensitizers employed in cancer treatment, describing their underlying mechanisms and structure‐activity relationship in terms of sonodynamic therapy. The significance of nanotechnology and combination therapy with other oncological modalities (photothermal therapy, photodynamic therapy, etc.)
Yuhan Ding, Yuchen Yang, Omer Aras, Feifei An, Mengjiao Zhou, Yichao Chai   +5 more
wiley   +1 more source

Lupenone preserves T cell activity by recovery of CD40L expression and protection from cytotoxicity due to methamphetamine exposure. [PDF]

PLoS One
Lee HS, Kim EN, Jeong GS.
europepmc   +1 more source

iPRISM: Intelligent Predicting Response to Cancer Immunotherapy through Systematic Modeling

Advanced Intelligent Systems, EarlyView.
The Intelligent Predicting Response to cancer Immunotherapy through Systematic Modeling (iPRISM) model uses data from genes and immune responses to predict how well cancer patients will respond to immunotherapy. Tested on multiple cancer types, iPRISM shows higher accuracy compared to existing methods.
Yinchun Su, Siyuan Li, Qian Wang, Bingyue Pan, Jiyin Lai, Guangyou Wang, Junwei Han, Qingfei Kong   +7 more
wiley   +1 more source

Natural Killer Cell-Secreted IFN-γ and TNF-α Mediated Differentiation in Lung Stem-like Tumors, Leading to the Susceptibility of the Tumors to Chemotherapeutic Drugs. [PDF]

Cells
Kaur K, Celis AP, Jewett A.
europepmc   +1 more source

Effect of delayed isolation of peripheral blood mononuclear cells on cell viability and functionality. [PDF]

BMC Immunol
Lehle S, Völkl S, Seitz K, Goossens C, Emons J, Ruebner M, Uhrig S, Ziegler P, Theuser AK, Beckmann MW, Fasching PA, Huebner H.   +11 more
europepmc   +1 more source

The immunological mouse mutants nude (nu) and rhino (hr rh ) generate cytotoxic effector cells following adoptive immunotherapy but fail to reject a transplanted tumor

, 1988
Robert Evans, TheodoreM. Duffy, LeonardD. Shultz   +2 more
openalex   +1 more source

Short-term oral zinc supplementation enhances Natural Killer cell functionality and decreases circulating Innate Lymphoid Cell counts and frequencies in healthy young adults. [PDF]

J Transl Med
Amling L, Rink L, Bennstein SB.
europepmc   +1 more source

TP53‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah, Daniel A. Arber, Devendra K. Hiwase   +2 more
wiley   +1 more source

High-throughput drug screening identifies SMAC mimetics as enhancers of NK-cell cytotoxicity in chronic myeloid leukemia.

Blood
Nygrén P, Bouhlal J, Jokinen E, Forstén S, Laajala E, Dias D, Adnan-Awad S, Ianevski A, Klievink J, Lähteenmäki H, Kuusanmäki H, Myllymäki M, Kasanen T, Saeed K, Lee DA, Hjorth-Hansen H, Aittokallio T, Dufva O, Mustjoki S.   +18 more
europepmc   +1 more source

NK Count and Natural Cytotoxicity in Immune Nonresponders Versus Responders Living With HIV. [PDF]

J Med Virol
Silvestre C, Tuaillon E, Duroyon MM, Abrantes M, Thibout JC, Villalba M, Picot MC, Gross A, Makinson A.   +8 more
europepmc   +1 more source