Results 291 to 300 of about 55,236 (336)

A distinct subset of stem-cell memory is poised for the cytotoxicity program in CD4⁺ T cells in humans. [PDF]

Sci Adv
Kar R, Sinha S, Khatun Z, Sharma A, Patil VS.   +4 more
europepmc   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

When checkpoint inhibitors break barriers: Mechanisms and challenges of irAEs of the skin, gastrointestinal tract, and lung. [PDF]

Clin Cancer Res
Sinha A, Seervai RNH, Vlastelica KM, Fisher Thomas M, Hornick NI.   +4 more
europepmc   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Synergistic potential of sipuleucel-T in enhancing immunotherapy for metastatic castration-resistant prostate cancer. [PDF]

J Immunother Cancer
Rawat K, Punia V, Mathews P, McCoy S, Song W, Saeed MA, Pachynski RK.   +6 more
europepmc   +1 more source

Commentary on differential impact of TIM-3 ligands on NK cell function. [PDF]

J Immunother Cancer
van de Ven R.
europepmc   +1 more source

Anthracycline selection in drug-eluting-beads-transarterial chemoembolization (DEB-TACE) for hepatocellular carcinoma: emerging evidence for idarubicin. [PDF]

Hepatobiliary Surg Nutr
Makary MS.
europepmc   +1 more source

Xenotransplantation Literature Update: January-June 2025. [PDF]

Xenotransplantation
Shirini K, Ladowski JM, Meier RPH.
europepmc   +1 more source

Switching On Gene Therapy for Allergic Rhinitis: The AAVITS Approach. [PDF]

Am J Respir Cell Mol Biol
Jia H.
europepmc   +1 more source

Low dose photodynamic therapy promotes a cytotoxic immunological response in a murine model of malignant pleural mesothelioma

, 2019
Sabrina Cavin, Julien Faget, Aspasia Gkasti, Hao You, Etienne Meylan, Jean Yannis Perentes   +5 more
openalex   +1 more source