Results 331 to 340 of about 880,908 (352)
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Viral-bacterial pneumonia in calves: effect of bovine herpesvirus-1 on immunologic functions.
Journal of Infectious Diseases, 1985The temporal relation between a lung infection with bovine herpesvirus-1, suppression of some immune functions, and susceptibility to secondary bacterial infection resulting in fibrinous pneumonia prompted a study to determine the mechanism(s) involved ...
H. Bielefeldt Ohmann, L. Babiuk
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A longitudinal study of immunological parameters in multiple sclerosis
Journal of the Neurological Sciences, 1979Complement-dependent gliotoxic antibody activity was determined in 22 patients with multiple sclerosis (MS) and 19 normal control persons. Peripheral blood serum was collected from MS patients at about 4-week intervals for one year, and the results of cytotoxicity tests correlated with the course of disease.
Toni Gradl, Pearl Mar, Christa Dörner
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Immunologically Mediated Cytotoxicity against Human Eye Muscle Cells in Graves’ Ophthalmopathy*
The Journal of Clinical Endocrinology & Metabolism, 1986The possible roles of antibody-mediated complement-dependent cytotoxicity (AMC), antibody-dependent killer (K) cell-mediated cytotoxicity (ADCC), and spontaneous, natural killer (NK) cell-mediated cytotoxicity (NKC) against human eye muscle cells in the pathogenesis of Graves' ophthalmopathy were investigated, using as targets human eye muscle cells ...
J. How +5 more
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Studies on the mechanism of antibody-dependent polymorphonuclear leukocyte-mediated cytotoxicity.
Journal of Immunology, 1977Human polymorphonuclear leukocytes (PMN) were cytotoxic to mammalian tumor cells (LSTRA) in the presence of anti-LSTRA serum as determined by a 51Cr release assay.
R. Clark, S. Klebanoff
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An immunological suppressor cell inactivating cytotoxic T-lymphocyte precursor cells recognizing it
Nature, 1980The immune system does not normally react against self components. Originally, it was postulated that self-reactive cells were somehow deleted or blocked. More recent thinking is that such cells are suppressed by regulatory networks similar to those limiting the immune response against non-self determinants. Both mechanisms may exist. I describe here a
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A Novel Flow Cytometric Assay for Evaluating Cell-Mediated Cytotoxicity
Journal of immunotherapy, 2005Comprehensive evaluation of cell-mediated cytotoxicity is very important, especially in the clinical setting, when a surrogate immunologic endpoint that correlates with a clinical outcome needs to be defined.
Mark W. Burkett +4 more
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A Reappraisal of Cytotoxic Lymphocytes in Human Tumor Immunology
1987Extensive work done at the Section of Clinical Tumor Virology and Immunology, Department of Medicine, The University of Texas M. D. Anderson Hospital, from 1968 to 1978 on the cytotoxicity of lymphocytes to cultured human tumor cells is reviewed. The early results and concepts are now reinterpreted in the light of newer knowledge generated worldwide in
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HIV-specific cytotoxic T-lymphocyte activity in immunologically normal HIV-infected persons
AIDS, 1998CD8+ T-cell counts usually increase soon after infection with HIV, whereas CD4+ cell counts decrease. The result of these changes in T-cell subpopulation subsets in most HIV-infected subjects is inversion of the CD4 : CD8 ratio from greater than 1.0 typical of uninfected persons to less than 1.0 after infection.Six HIV-infected individuals were ...
Famane Chung +5 more
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Immunological Studies in Human Schistosomiasis
The American Journal of Tropical Medicine and Hygiene, 1977Complement dependent cytotoxic antibodies for Schistosoma mansoni schistosomules were studied in a Brazilian population. The sera of S. mansoni-infected patients gave a high percentage of cytotoxicity (63.4%) compared with sera from persons not infected (8.7%). The IgG class and the specificity of these cytotoxic antibodies are defined.
Capron, Monique +4 more
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International Archives of Allergy and Immunology, 1980
Rabbits immunized with a saline extract of intestinal tissue in complete Freund’s adjuvant produce antibody which mediates complement-dependent cytotoxicity for colon epithelial cells <i>in vitro</i>. The presence of this antibody did not correlate with histologic alterations of the colon in the immunized rabbits.
Ellen Herrington, Bruce S. Rabin
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Rabbits immunized with a saline extract of intestinal tissue in complete Freund’s adjuvant produce antibody which mediates complement-dependent cytotoxicity for colon epithelial cells <i>in vitro</i>. The presence of this antibody did not correlate with histologic alterations of the colon in the immunized rabbits.
Ellen Herrington, Bruce S. Rabin
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