Results 341 to 350 of about 880,908 (352)
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Critical Reviews in Immunology, 2015
A synapse is a specialized structure that forms when the plasma membrane of two cells come into close contact to facilitate communication and signaling. Cells of the immune system form 'immunological' synapses that have an ordered structure and are essential for immune cell activation, function and homeostasis.
Phillip K. Darcy +3 more
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A synapse is a specialized structure that forms when the plasma membrane of two cells come into close contact to facilitate communication and signaling. Cells of the immune system form 'immunological' synapses that have an ordered structure and are essential for immune cell activation, function and homeostasis.
Phillip K. Darcy +3 more
openaire +2 more sources
Annual Review of Immunology, 1996
Studies with perforin-deficient mice have demonstrated that two independent mechanisms account for T cell–mediated cytotoxicity: A main pathway is mediated by the secretion of the pore-forming protein perforin by the cytotoxic T cell, whereas an alternative nonsecretory pathway relies on the interaction of the Fas ligand that is upregulated during T ...
Rolf M. Zinkernagel +4 more
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Studies with perforin-deficient mice have demonstrated that two independent mechanisms account for T cell–mediated cytotoxicity: A main pathway is mediated by the secretion of the pore-forming protein perforin by the cytotoxic T cell, whereas an alternative nonsecretory pathway relies on the interaction of the Fas ligand that is upregulated during T ...
Rolf M. Zinkernagel +4 more
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Cell-Mediated Cytotoxicity to Muscle in Polymyositis
, 1973Immunologic injury to cultures of skeletal muscle was studied in patients with polymyositis by means of a 51Cr release method that allows quantitation of myocyte injury. Lymphocyte-mediated myotoxicity was elevated in a group of nine patients with active
R. Dawkins, F. Mastaglia
semanticscholar +1 more source
, 1988
In postinflammatory hypopigmentation and in vitiligo, one observes histologic evidence of melanocyte damage, disappearance of melanocytes, and clinical loss of pigmentation. In the case of vitiligo, this loss of pigment is complete. There is considerable
D. Norris +6 more
semanticscholar +1 more source
In postinflammatory hypopigmentation and in vitiligo, one observes histologic evidence of melanocyte damage, disappearance of melanocytes, and clinical loss of pigmentation. In the case of vitiligo, this loss of pigment is complete. There is considerable
D. Norris +6 more
semanticscholar +1 more source
Immunoselection of tumor variants resistant to antibody-mediated cytotoxicity
Cancer Immunology Immunotherapy, 1982The immunological characteristics of two series of metastatic variants of restricted genetic origin were related to their lung-colony-forming potential. A series of metastatic variants was isolated from a tumor-cell population in which heterogeneity appeared following short-term in vivo passage, while a second series of variants were immunoselected in ...
William C. Davis +2 more
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Virchows Archiv A Pathological Anatomy and Histopathology, 1991
To clarify the immune mechanism of cytotoxicity in acute cardiac allograft rejection, we observed interactions between cardiocytes and mononuclear cells using immunohistochemistry and light and electron microscopy. All allografted WKA rat hearts transplanted to F344 recipients stopped beating by the 7th day after the transplantation.
Keishiro Kawamura +5 more
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To clarify the immune mechanism of cytotoxicity in acute cardiac allograft rejection, we observed interactions between cardiocytes and mononuclear cells using immunohistochemistry and light and electron microscopy. All allografted WKA rat hearts transplanted to F344 recipients stopped beating by the 7th day after the transplantation.
Keishiro Kawamura +5 more
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The Influence of Ultraviolet Light on Immunological Cytotoxicity in the Skin
Photochemistry and Photobiology, 1997David A. Norris +3 more
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Recognition of human tumours: viral antigens as immunological targets for cytotoxic T cells
2001It has been estimated that some 15% of human cancers are associated with viral infection and the use of more sensitive molecular techniques may well reveal more. Preventing viral infection using prophylactic vaccines would dramatically decrease cancer incidence, particularly in developing countries.
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Clinical and immunological significance of human melanoma cytotoxic antibody
Plastic and Reconstructive Surgery, 1975openaire +2 more sources