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Herein, we show that profound afferent long-term peanut-allergen-specific IgE immunological tolerance for 3 to 9 months induced sustained unresponsiveness (SU) in naïve or peanut-sensitized rodents after peanut allergen immunization. Rodents were vaccinated sublingually with a peanut allergen extract or recombinant peanut allergen in chenodeoxycholate (
Swey-Shen Chen +4 more
openaire +3 more sources
Sensitization, Immunological Tolerance and Desensitization of Guinea Pigs to Neoarsphenamine II.
J.R. Frey, A.L. de Weck, H. Geleick
+5 more sources
P8.120: Impact of Desensitization in Immunological Low-Risk Patients in Kidney Transplantation
Youngmin Ko +4 more
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CASE REPORT: Immunological Aspects of Oral Desensitization in Food Allergy
E. Nucera +6 more
+4 more sources
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Journal of Pediatric Endocrinology & Metabolism (JPEM), 2021
Objectives Enzyme replacement therapy (ERT) with alglucosidase alfa (rhGAA) has changed the fatal course of infantile Pompe disease, however, development of anti rhGAA antibodies and infusion-associated reactions (IAR) restrict the tolerability and ...
Merve Emecen Şanlı +7 more
semanticscholar +1 more source
Objectives Enzyme replacement therapy (ERT) with alglucosidase alfa (rhGAA) has changed the fatal course of infantile Pompe disease, however, development of anti rhGAA antibodies and infusion-associated reactions (IAR) restrict the tolerability and ...
Merve Emecen Şanlı +7 more
semanticscholar +1 more source
As previously reported, LPS and 8-derivatized guanosine (both generators of IL-1 release), as well as IL-1 itself interfere with the in vivo induction of tolerance to DHGG in A/J mice.
William O. Weigle +3 more
openalex +2 more sources
E. Kim, B. Vickery, A. Radwan, W. Burks
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Immunological aspects of oral desensitization in food allergy.
Digestive diseases and sciences, 2000IMMUNOLOGY ASPECTS OF ORAL DESENSITIZATION IN FOOD ...
Nucera, Eleonora +6 more
openaire +4 more sources
Insulin allergy. Clinical and immunological effects of specific desensitization
Acta Diabetologica Latina, 1969Five patients with insulin allergy were desensitized with porcine insulin according to the method of Urbach and Gotlieb. The diagnosis of insulin allergy was based on clinical manifestations, positive skin tests, and, moreover, on positive Prausnitz-Kustner (P.K.) reactions in 2 cases. Successful desensitization was obtained in 3 cases.
openaire +2 more sources
Patient and Graft Outcome Among High Immunologic Risk Renal Transplant Recipients
Transplantation, 2018Introduction Kidney transplantation (KT) is the preferred treatment for ESRD. However, some patients had prior HLA sensitization making them immunologically high risk for graft rejection and poorer graft survival.
J. Mora +3 more
semanticscholar +1 more source

