Results 201 to 210 of about 163,628 (307)

Update on occupational contact urticaria: a systematic narrative review. [PDF]

Curr Opin Allergy Clin Immunol
Bizjak-Suran M, Jørgensen IL, Alfonso JH.   +2 more
europepmc   +1 more source

Combinations of type 1 diabetes, celiac disease and allergy : An immunological challenge

, 2011
The immune system is composed of a complex network of different cell types protecting the body against various possible threats. Among these cells are T-helper (Th) cells type 1 (Th1) and type 2 (Th2), as well as T regulatory (Treg) cells. Th1 and Th2 are supposed to be in balance with each other, while Tregs regulate the immune response, by halting it
openaire   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Wheat Allergy: Clinical Phenotypes, Diagnostic Approaches, and Management Strategies. [PDF]

Allergy Asthma Immunol Res
Park JW, Park KH, Lee JH.
europepmc   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Association of maternal immunoglobulin G levels with pregnancy outcomes in primary immunodeficiency: A retrospective single-center study. [PDF]

Medicine (Baltimore)
Gerek ME, Çölkesen F, Türen Demir E, Önalan T, Sağun F, Akkuş FA, Kilinç M, Sadi Aykan F, Kahraman S, Arslan Ş.   +9 more
europepmc   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Multidimensional characterization of allergic rhinitis in Mysuru, South India: A cluster-based approach. [PDF]

J Allergy Clin Immunol Glob
Mahesh PA, Praveena AS, Kaleem Ullah M, Greeshma MV, Siddaiah JB, Daniel J, Christopher DJ, Nirantharakumar K, Mansur AH, Scadding G, Wraith DC, Krishna MT.   +11 more
europepmc   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

IL12RB1 Deficiency Appearing in North America: Expanding the Clinical Phenotypes. [PDF]

Clin Infect Dis
Wang C, Marciano BE, Harris AJ, Johnston AM, Apaydin Arikan E, Bayer DK, Solomon BD, Price NB, Platt CD, Modi AJ, Shaker MS, Seroogy CM, Johnson D, Kleiner DE, Chirombo Kluczynski L, Anderson VL, Daub JR, Berghout J, Oler AJ, Walkiewicz MA, Similuk M, Lewis DB, Galgiani JN, Freeman AF, Rosen LB, Hsu AP, Zerbe CS, Holland SM.   +27 more
europepmc   +1 more source