Results 41 to 50 of about 163,628 (307)

Distinguishing Asthma Phenotypes Using Machine Learning Approaches. [PDF]

, 2015
Asthma is not a single disease, but an umbrella term for a number of distinct diseases, each of which are caused by a distinct underlying pathophysiological mechanism. These discrete disease entities are often labelled as asthma endotypes.
A Custovic, A Custovic, A Fraser, A Høst, A Pickles, A Simpson, A Wijga, Adnan Custovic, AJ Lowe, AV Berg, B Clarisse, BD Spycher, BD Spycher, BD Spycher, BG Toelle, BL Jones, BL Jones, C-M Chen, CA Figueiredo, CE Kuehni, CJ Lodge, CL Storr, D Barber, D Belgrave, D Caudri, D Nagin, DA Linzer, DC Belgrave, DC Belgrave, DCM Belgrave, DCM Belgrave, F Kauffmann, F Kauffmann, FD Martinez, FL Garden, FP Perera, G Bochenek, G Weinmayr, GB Marks, GP Anderson, J Hagenaars, J Henderson, J Lotvall, J Magidson, J Sunyer, J Winn, JA Smith, JK Vermunt, K Burnham, KE Wonderen Van, KL Nylund, L García-Marcos Álvarez, L Hunt, L Lowe, L Panico, LA Lowe, M Depner, M Herr, M Scott, Magnus Rattray, Mattia Prosperi, MJ Ege, ML Barreto, MM Hagendorens, MW Pijnenburg, N Lazic, NC Nicolaou, NG Papadopoulos, OE Savenije, P Burney, P Haldar, P Rzehak, P Rzehak, PD Sly, Q Chen, Q Vuong, Rebecca Howard, RJP Valk van der, RL Bergmann, RL Miller, RO Crapo, RT Stein, S American Thoracic, S Havstad, S Mihrshahi, S Rabe-Hesketh, S Stanojevic, SE Wenzel, SK Weiland, ST Lanza, ST Lanza, T Jung, T Minka, The European Community Respiratory Health Survey, V Siroux, WC Moore, X Robin, Y Lo   +97 more
core   +2 more sources

Frequency, distribution and immunologic nature of infusion reactions in subjects receiving pegloticase for chronic refractory gout

Arthritis Research & Therapy, 2017
Background To assess frequency and distribution of infusion reactions (IRs) in responders and nonresponders in randomized clinical trials (RCTs) of intravenous pegloticase and the utility of the National Institute of Allergy and Infectious Disease/Food ...
Leonard H. Calabrese, Arthur Kavanaugh, Anthony E. Yeo, Peter E. Lipsky   +3 more
doaj   +1 more source

New Indications of Biological Drugs in Allergic and Immunological Disorders: Beyond Asthma, Urticaria, and Atopic Dermatitis

Biomedicines, 2023
Asthma, chronic urticaria, and atopic dermatitis are some of the most numerous allergic diseases affecting children. Recent advances in the understanding of their specific intracellular molecular pathways have led to the approval of monoclonal antibodies
Daniele Russo, Paola Di Filippo, Sabrina Di Pillo, Francesco Chiarelli, Marina Attanasi   +4 more
doaj   +1 more source

Human Schistosome Infection and Allergic Sensitisation [PDF]

, 2012
Several field studies have reported an inverse relationship between the prevalence of helminth infections and that of allergic sensitisation/atopy. Recent studies show that immune responses induced by helminth parasites are, to an extent, comparable to ...
Mutapi, Francisca, Rujeni, Nadine, Taylor, David W.   +2 more
core   +3 more sources

Clinical profiles of patients with wheat-induced anaphylaxis at various ages of onset

World Allergy Organization Journal, 2023
Background: Wheat-induced anaphylaxis (WIA) is a serious and potentially life-threatening wheat allergy, more common in adults than in children. Little is known about the differences in clinical profiles in WIA among patients of various ages in China ...
Zhirong Du, PhD, Lun Li, MD, Juan Liu, PhD, Yingyang Xu, PhD, Le Cui, PhD, Jia Yin, MS   +5 more
doaj   +1 more source

Allergic and immunologic evaluation of children with celiac disease

Frontiers in Pediatrics
IntroductionCeliac disease (CD) and allergic diseases are immune-mediated disorders with overlapping clinical and immunologic features. The association between CD and selective immunoglobulin (Ig) A deficiency (sIgAD) is well-established, but limited ...
Duygu Demirtaş Güner, Kübra Baskın
doaj   +1 more source

Persistent effects of early infant diet and associated microbiota on the juvenile immune system. [PDF]

, 2015
Early infant diet has significant impacts on the gut microbiota and developing immune system. We previously showed that breast-fed and formula-fed rhesus macaques develop significantly different gut microbial communities, which in turn are associated ...
Ardeshir, Amir, Hartigan-O'Connor, Dennis J, Lu, Ding, Méndez-Lagares, Gema, Narayan, Nicole R, Van Rompay, Koen KA   +5 more
core   +1 more source

Changes of allergic inflammation and immunological parameters after Alt a 1 and A. alternata immunotherapy in mice

World Allergy Organization Journal, 2023
Background: The efficacy of allergen-specific subcutaneousimmunotherapy (SCIT) with Alt a 1 of the fungus A. alternata is still unknown. Yet, few studies compare the therapeutic effects and immunological mechanisms of Alt a 1 and A.
Juan Liu, Junda Li, Jia Yin
doaj   +1 more source

Chronic rhinosinusitis with nasal polyps in older adults : clinical presentation, pathophysiology, and comorbidity

, 2019
Purpose of Review Chronic rhinosinusitis and nasal polyps (CRSwNP) is a common condition that significantly affects patients' life. This work aims to provide an up-to-date overview of CRSwNP in older adults, focusing on its aging-related clinical ...
Bachert, Claus, Lee, Ji-Hyang, Song, Woo-Jung, Won, Ha-Kyeong   +3 more
core   +2 more sources

Time to First-Line ART Failure and Time to Second-Line ART Switch in the IeDEA Pediatric Cohort [PDF]

, 2018
BACKGROUND: Globally, 49% of the estimated 1.8 million children living with HIV are accessing antiretroviral therapy (ART). There are limited data concerning long-term durability of first-line ART regimens and time to transition to second-line ...
Ayaya, Samuel, Davies, Mary-Ann, Edmonds, Andrew, Leroy, Valériane, Li, Shanshan, Marete, Irene, Mofenson, Lynne M., Musick, Beverly S., Newman, Jamie E., Nguyen, Lam Van, Obama, Marie-Thérèse, Sawry, Shobna, Sohn, Annette H., Tanoh Eboua, François, Wools-Kaloustian, Kara, Yiannoutsos, Constantin T., Yotebieng, Marcel   +16 more
core   +2 more sources