Results 161 to 170 of about 275,636 (273)

In Vivo‐Like Scaffold‐Free 3D In Vitro Models of Muscular Dystrophies: The Case for Anchored Cell Sheet Engineering in Personalized Medicine

Advanced Healthcare Materials, EarlyView.
The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi, John Cappuccitti   +1 more
wiley   +1 more source

Comments on "Baricitinib versus tocilizumab in mechanically ventilated patients with COVID-19: a nationwide cohort study". [PDF]

Crit Care
Li R, Wang J, Li Q, Guo Q, Zhao JK, Wei JC, Zhang LY.   +6 more
europepmc   +1 more source

Tyrosine-Phosphorylation-Dependent Translocation of the SLAT Protein to the Immunological Synapse Is Required for NFAT Transcription Factor Activation [PDF]

, 2008
Stéphane Bécart, Ann J. Canonigo-Balancio, Céline Charvet, Sonia Feau, Caitlin Sedwick, Amnon Altman   +5 more
openalex   +1 more source

Short‐Chain Fatty Acids Modulate Anti‐ROR1 CAR T‐Cell Function and Exhaustion in an Intestinal Adenocarcinoma‐on‐Chip Model

Advanced Healthcare Materials, EarlyView.
Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner, Adrian Feile, Miriam Alb, Michael Hudecek, Philip Hewitt, Alexander S. Mosig   +5 more
wiley   +1 more source

Gut microbiota metabolites impact immunologic responses to antiretroviral therapy in HIV-infected men who have sex with men. [PDF]

Infect Dis Poverty
Feng A, Zhao H, Qiu C, Luo D, Wu H, Meng X, Li L, Zou H.   +7 more
europepmc   +1 more source

Epithelioid cell-type melanoma as a prognostic factor of poor response to immunological treatment

, 2000
P.A. Ascierto, N Mozzillo, Corrado Caracò, Rosanna Parasole, Giuseppe Palmieri, Maria Teresa Melucci, Gerardo Botti, Giuseppe Castello   +7 more
openalex   +1 more source

Immunologic and Biochemical Factors of Coincident Celiac Disease and Type 1 Diabetes Mellitus in Children [PDF]

, 2008
Małgorzata Myśliwiec, Anna Balcerska, Katarzyna Zorena, Jolanta Myśliwska, Piotr Wiśniewski   +4 more
openalex   +1 more source

Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro‐Inflammatory Macrophage Activation

Advanced Healthcare Materials, EarlyView.
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth, Zachary S.C.S. Froom, Natasha D. Osborne, Christian N. Rempe, Brenden Wheeler, Kyle Medd, Neal I. Callaghan, Huikang Qian, Abhinav P. Acharya, Carlie Charron, Locke Davenport Huyer   +10 more
wiley   +1 more source

Microcirculation and intravascular imaging assessment in heart transplant recipients for detection of cardiac allograft vasculopathy: a pilot study. [PDF]

Postepy Kardiol Interwencyjnej
Hawranek M, Liszka R, Kuczaj A, Pyka Ł, Wróbel M, Herdyńska-Wąs M, Gąsior M, Przybyłowski P.   +7 more
europepmc   +1 more source

Hyperhomocyst(e)inemia is an important non-immunologic factor that induces accelerated transplant vascular sclerosis in syngeneic and allogeneic cardiac transplant grafts in rats

, 2000
Judith W. Cook, Qiang Yin, Tammy V. de le Melena, Rene M. Malinow, Susan L. Orloff   +4 more
openalex   +1 more source