Results 261 to 270 of about 127,185 (292)
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Molecular Immunology of Factor VIII
Annual Review of Medicine, 1974Molecular immunology has served to better characterize the molecular defects underlying the two principal inherited abnormalities of Factor VIII-classic hemo philia and von Willebrand's disease. Of particular significance has been the ability of specific antibodies to detect Factor VIII molecules that are partially or totally deficient in their ...
T S, Zimmerman, T S, Edgington
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Immunologic Factors in Pernicious Anemia
Postgraduate Medicine, 1967Pernicious anemia may be congenital or acquired. The congenital form is rare. The acquired form usually occurs in persons over 50 years of age. Autoantibody directed against intrinsic factor is present in the majority of patients and is considered to be diagnostic of pernicious anemia.
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AN IMMUNOLOGICAL FACTOR IN EPILEPSY
The Lancet, 1976It is proposed that epileptic discharges could be the result of an autoimmune response to either an antigen released during tissue destruction or an infective agent. A possible mechanism involves the blocking by antibodies of transmitter receptor sites at synapses, whereby synaptic transmission is reduced.
G, Ettlinger, M B, Lowrie
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Chemokines: immunology's high impact factors
Nature Immunology, 2001Chemokines facilitate leukocyte migration and positioning as well as other processes such as angiogenesis and leukocyte degranulation. The burgeoning knowledge on chemokines and their receptors has influenced many aspects of immunology, in part because cell migration is intimately related to leukocyte function.
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Thrombosis and Haemostasis, 1971
SummaryA monospecific antiserum against factor X was prepared in rabbits. The antiserum precipitated factor X in human plasma and serum and monkey serum. The antiserum was used to :1. demonstrate the presence of factor X precursor in blood from patients under anticoagulant therapy,2.
H, Prydz, A, Gladhaug
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SummaryA monospecific antiserum against factor X was prepared in rabbits. The antiserum precipitated factor X in human plasma and serum and monkey serum. The antiserum was used to :1. demonstrate the presence of factor X precursor in blood from patients under anticoagulant therapy,2.
H, Prydz, A, Gladhaug
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Immunology of Factor VIII Inhibitors
Seminars in Thrombosis and Hemostasis, 2002Why some patients with hemophilia A produce inhibitory antibodies is not known. However, many new findings both in the mechanisms of immune tolerance and in the understanding of the mechanisms by which antibodies interact with the factor VIII molecule are converging toward an integrated picture of what tolerance to factor VIII represents.
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Immunological Factors in Vascular Diseases
1978It is generally accepted that arteriosclerosis is a polyaetiologic and presumably polypathogenetic disease caused by a combination of individually different factors. From the considerable amount of informations obtained in the last 10–15 years, it seems likely that allergic and autoimmune processes may also play a role in the chain of events leading to
S, Gerö +4 more
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Immunological factors in organ transplantation
Intensive Care Medicine, 1989Several immunological factors affect the outcome of human kidney transplants. HLA-A, -B and -DR matching improves kidney graft survival rate, especially matching for HLA-DR antigens. The beneficial effect of pretransplant blood transfusion has been confirmed although the mechanisms of the beneficial effect are not clear.
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Immunological and Endocrine Factors
1978The two best understood immunological mechanisms are those associated with humoral and cellular immunity. Humoral immunity is the production of soluble antibodies against antigens, commonly bacterial toxins. These antibodies appear in the serum as gamma globulins.
Kenneth C. Calman, John Paul
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Chronic graft loss. Immunological and non-immunological factors.
Contributions to nephrology, 2004Late loss of kidney grafts is an ongoing problem in the field of transplantation. This is caused by immunological and non-immunological factors, the main immunological driver of rejection is the immune response against HLA molecules that differ between donor and recipient.To measure the anti-donor responses that a recipient can mount, we have been ...
Maria P, Hernandez-Fuentes +1 more
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