Results 91 to 100 of about 75,193 (298)
Gammaherpesvirus-infected germinal center cells express a distinct immunoglobulin repertoire
Life Science Alliance, 2020 Germinal center B cells infected with gammaherpesvirus display altered repertoire with biased usage of lambda light chain and skewed utilization of IGHV genes.
Monika A Zelazowska +6 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham +11 more
wiley +1 more source
A dual nature of γδ T cell immune memory responses
eLifeImmune memory was considered for decades an exclusive hallmark of the adaptive immune response. However, recent studies have revealed that innate immune cells can also ‘recall’ information of a primary insult during infection or vaccination and deploy ...
Tsz Kin Suen +5 more
doaj +1 more source
Involvement of memory T-cells in the pathophysiology of chronic lymphocytic leukemia
Revista Brasileira de Hematologia e Hemoterapia, 2014 The role of T-cells in the pathogenesis of chronic lymphocytic leukemia has recently gained much attention due to the importance of the constant interaction between neoplastic B-cells with microenvironment substratum and T-cells.
Rodolfo Patussi Correia +5 more
doaj +1 more source
Modelling Immunological Memory [PDF]
, 2007 26 pages, In Silico ...
Garret, S +4 more
openaire +4 more sources
Immune response to vaccines in children with celiac disease [PDF]
, 2017 Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and ...
ANANIA, Caterina +4 more
core +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
The role of environmental factors in modulating immune responses in early life
Frontiers in Immunology, 2014 The concept of immunological memory stipulates that past exposures shape present immune function. These exposures include not only specific antigens impacting adaptive immune memory, but also conserved pathogen or danger associated molecular patterns ...
Duncan Malcolm MacGillivray +1 more
doaj +1 more source
Pathogenesis of feline enteric coronavirus infection. [PDF]
, 2008 Fifty-one specific pathogen-free (SPF) cats 10 weeks to 13 years of age were infected with a cat-to-cat fecal-oral passed strain of feline enteric coronavirus (FECV). Clinical signs ranged from unapparent to a mild and self-limiting diarrhea. Twenty-nine
Allen, Claire E +2 more
core
Early Investigations and Recent Advances in Intraperitoneal Immunotherapy for Peritoneal Metastasis. [PDF]
, 2018 Peritoneal metastasis (PM) is an advanced stage malignancy largely refractory to modern therapy. Intraperitoneal (IP) immunotherapy offers a novel approach for the control of regional disease of the peritoneal cavity by breaking immune tolerance.
Bowne, Wilbur B. +5 more
core +2 more sources