Results 201 to 210 of about 43,875 (259)

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

Atypical memory B cell clonal expansion and inflammatory programs associate with platelet-activating antibody development in COVID-19. [PDF]

JCI Insight
Witman N, Yu M, Zhang Y, Gai K, Chen Y, Zhou L, Nguyen C, Zhu W, Zheng Y, Jobe S, Graham MB, Cui W, Wang D, Wen R.   +13 more
europepmc   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

CHORIORETINITIS AFTER BACILLUS CALMETTE-GUERIN TREATMENT FOR BLADDER CANCER. [PDF]

Retin Cases Brief Rep
Boopathiraj N, Boopathiraj N, Wagner IV, Powers R, Mashayekhi A.   +4 more
europepmc   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Predicting Durable Anti-tumor Immune Responses after Cancer Vaccines. [PDF]

J Cancer Immunol (Wilmington)
Liao JB, Disis ML.
europepmc   +1 more source

Persistent T Cell Immunity Following Nipah Virus Infection: Evidence From Malaysian Survivors. [PDF]

J Infect Dis
Ibrahim PAS, Ong HM, Cheong HC, Tan CT, Schee JP, Avumegah MS, Wong WF, Chang LY.   +7 more
europepmc   +1 more source

Maculopapular-Type Drug Eruption Caused by Cetuximab. [PDF]

Cureus
Ikegawa N, Saito-Sasaki N, Sawada Y.
europepmc   +1 more source

Beyond cytokine blockade: could CAR-Tregs open a new era of tissue-targeted immune tolerance in psoriatic arthritis? [PDF]

Front Immunol
Queiro R, Alonso S, Alperi M.
europepmc   +1 more source

Regulatory T-cells in Reproductive Medicine: Implications for Endometriosis-Associated Infertility and Implantation Immunity. [PDF]

Cureus
Taguchi S, Hayashi T.
europepmc   +1 more source