Results 231 to 240 of about 75,193 (298)

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Characterization of elite controllers with an undetectable intact HIV DNA reservoir. [PDF]

J Clin Invest
Blazkova J, Kennedy BD, Justement JS, Shi V, Sewack A, Manning MR, Dasari S, Gittens K, Moir S, Connors M, Migueles SA, Chun TW.   +11 more
europepmc   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Natural and Vaccine-Induced Immunity in the Post-Pandemic Era: Convergence, Divergence, and Unfinished Challenges. [PDF]

Vaccines (Basel)
Dimeglio C.
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Persistent Seronegativity and Absence of Intact Proviruses Despite Prolonged Initial Viremia in Early-Treated Perinatal HIV Infection. [PDF]

Open Forum Infect Dis
Charre C, Buseyne F, Mélard A, Gardiennet E, Mariaggi AA, Montange T, Le Chenadec J, Warszawski J, Blanche S, Avettand-Fenoël V, Frange P.   +10 more
europepmc   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Peripheral Immune Remodeling After Spinal Cord Injury: Marked by Expansion of CD38⁺, CTLA-4⁺, and PD-1⁺ T and NK Cells. [PDF]

Neurol Neuroimmunol Neuroinflamm
Veeningen N, Añé-Kourí AL, Pues A, Rubio S, Fraussen J, Ioannou C, Martens DS, van Laake-Geelen CCM, Deckers J, Cornips EMJ, Bamps S, Gysemberg G, Van Broeckhoven J, Hellings N, Slaets H.   +14 more
europepmc   +1 more source

Ultrasmall Fe‐curcumin immunomodulators reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence

BMEMat, EarlyView.
This work discovered a novel research that ultrasmall Fe‐curcumin immunomodulators could reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence. Abstract CAR‐T cell immunotherapy has achieved exciting success in hematologic malignancies, but the therapeutic efficacy is relatively limited in solid ...
Jiazhi Duan, Yuchan Xue, Miao Zhang, Zihao Zhang, Shiyu Peng, Minghao Sui, Han Ding, Yingying Nie, Yuemin Feng, Le Wang, Tianru Zhang, Mingchuan Yu, He Xia, Hong Liu, Qiang Zhu, Songbo Zhao   +15 more
wiley   +1 more source

Pre-vaccine immune profiling in cancer patients identifies correlates of COVID-19 vaccine responses. [PDF]

Hum Vaccin Immunother
Kazerani M, Mahov S, Foley J, Merin NM, Choi SY, Lownik J, Xu AM, Milshteyn L, Villamejor AL, Nadri M, Nguyen N, Kazemian E, Hamid O, Darrah J, Gong J, Paquette R, Vescio R, Mehmi I, Tourtellotte WG, Ramanujan VK, Reckamp KL, Figueiredo JC, Merchant A.   +22 more
europepmc   +1 more source