Results 61 to 70 of about 77,258 (311)
Cytotoxicity of Reparative Endodontic Cements on Human Periodontal Ligament Stem Cells
Objective: To compare the cytotoxicity of commercial reparative endodontic cements on human periodontal ligament stem cells (hPDLSCs). Material and Methods: The culture of hPDLSCs was established.
Marlus da Silva Pedrosa +4 more
doaj
Immunological methods in diagnosis of sarcoidosis end tuberculosis of lung
Differential diagnosis disseminated diseases provides sarcoidosis and tuberculosis. Frequency of mistakes consists over 40% [Visel AA, 2013]. That’s why including of new diagnosis methods is weary important.
M. А. Belokurov +9 more
doaj +1 more source
Testing the organization of the immunological synapse [PDF]
Upon encounter with antigen-bearing presenting cells, T cells initiate the formation of a unique junction termed the immunological synapse (IS). The morphology of this junction, characterized in EM as a series of discrete contacts into which are interspersed synaptic spaces [1], has multiple similarities to neuronal synapses.
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Diagnostic accuracy of 5 different brands of dengue virus non-structural protein 1 (NS1) antigen rapid diagnostic tests (RDT) in Indonesia. [PDF]
Indonesia is hyper-endemic for dengue. Dengue virus non-structural protein 1 (NS1) antigen detection is now increasingly used by clinicians in Indonesia to confirm dengue infection, but many available brands have not had any evaluation on their ...
Yohan, Benediktus +8 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Predicting Response to Polytrauma through Resolution of Immunologic Mediators
Background/Objective: Traumatic injury can lead to hemorrhagic shock and hypoperfusion in patients precipitating multiple organ dysfunction. This study adopts a precision medicine approach to identifying biological markers in predicting patient response ...
McKinley, Todd O., Ali, Iyad
core
The authors report a case in a 10.5 year old girl admitted to the Centre hospitalier Guy-de-Chauliac, Montpellier, France, with a left painful ophthalmoplegia.
J Gordon Millichap
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

