Results 61 to 70 of about 2,941,608 (313)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

PSYNDEX Tests Review für IT-M 5-7 - INFORMELLE TESTS - MUSIK 5-7

open access: yes, 1984
This is a PSYNDEX Tests Review of IT-M 5-7 - INFORMELLE TESTS - MUSIK 5-7. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Lukesch, Helmut
core   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

PSYNDEX Tests Review für BMT - BILDUNGSMOTIVATIONSTEST

open access: yes, 1988
This is a PSYNDEX Tests Review of BMT - BILDUNGSMOTIVATIONSTEST. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Kroiss, Josef
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

PSYNDEX Tests Review für MDT 8 - MATHEMATIK-DIDAKTISCHE TESTS FÜR DIE 8. SCHULSTUFE

open access: yes, 1983
This is a PSYNDEX Tests Review of MDT 8 - MATHEMATIK-DIDAKTISCHE TESTS FÜR DIE 8. SCHULSTUFE. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Lukesch, Helmut
core   +1 more source

Combination therapy with prednisone and cyclophosphamide in a 14-year-old boy with pemphigus foliaceus – a case report

open access: yesPrzegląd Dermatologiczny, 2017
Introduction . Pemphigus foliaceus is a dermatosis rarely occurring in the paediatric population. Objective. To draw attention to diagnostic and therapeutic difficulties associated with pemphigus foliaceus. Case report.
Magdalena Salińska   +4 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

PSYNDEX Tests Review für LFB-FOT - LEHRERFRAGEBOGEN ZUM EINSATZ FEHLERORIENTIERTER TESTS

open access: yes, 1989
This is a PSYNDEX Tests Review of LFB-FOT - LEHRERFRAGEBOGEN ZUM EINSATZ FEHLERORIENTIERTER TESTS. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Eberwein, Manfred
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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