Results 81 to 90 of about 1,437,121 (388)
Current Dermatology Reports, 2018 Purpose of ReviewChronic wounds are a tremendous burden on the healthcare system and lead to significant patient morbidity and mortality. Normal cutaneous wound healing occurs through an intricate and delicate interplay between the immune system ...
S. Ellis, Elaine J. Lin, D. Tartar
semanticscholar +1 more source
Cellular Immunology, 1979 Immunity to disease has long been recognized, but only during the late nineteenth century, thanks to Louis Pasteur, Robert Koch, Elie Metchnikoff and Paul Ehrlich, did immunology become a true science able to explain mechanisms and to develop preventive vaccines.
openaire +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Frontiers in EducationThe rapidly expanding knowledge base in immunology and its increasing significance in multiple research areas and healthcare underscore the need for more comprehensive undergraduate curricula that allow students to engage deeply with immunology-based ...
Chad R. Sethman, Kelly J. R. Collins
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Review of: "[Short Communication] Immunology of a Morbillivirus: Measles 1954 to 2023" [PDF]
, 2023 Sushila Maan
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A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Advanced application of bovine intestinal epithelial cell line for evaluating regulatory effect of lactobacilli against heat-killed enterotoxigenicEscherichia coli-mediated inflammation [PDF]
, 2013 Background: Previously, a bovine intestinal epithelial cell line (BIE cells) was successfully established. This work hypothesized that BIE cells are useful in vitro model system for the study of interactions of microbial- or pathogenassociated molecular ...
Alvarez, Gladis Susana +15 more
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Key role for inhibins in effective T cell activation, migration and Th17 differentiation
FEBS Open Bio, EarlyView.Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco +5 more
wiley +1 more source
Journal of Inflammation ResearchSimin Yuan,1 Wen Zhu,2 Yue Wang,1,2 Lili Yu1,3,4 1Faculty of Chinese Medicine, Macau University of Science and Technology, Macau, People’s Republic of China; 2Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of ...
Yuan S, Zhu W, Wang Y, Yu L
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