Results 21 to 30 of about 5,981,210 (344)

Rewilding immunology

, 2020
The common origin of all species provides a wealth of history recorded in DNA and a lens for understanding human biology. Immunology research has traditionally used rodents as the model of choice.
Flies, Andrew S, Wild Comparative Immunology Consortium   +1 more
core   +1 more source

Unhealthy landscapes: Policy recommendations on land use change and infectious disease emergence. [PDF]

, 2004
Anthropogenic land use changes drive a range of infectious disease outbreaks and emergence events and modify the transmission of endemic infections.
Patz, Jonathan A, Tabor, Gary M, A. Marm Kilpatrick, Daszak, Peter, Molyneux, David, Kilpatrick, A Marm, Jonathan A. Patz, David Molyneux, Peter Daszak, Bradley, David J, Mary Pearl, Johannes Foufopoulos, Nathan D. Wolfe, Working Group on Land Use Change and Disease Emergence, Epstein, Jon, A. Alonso Aguirre, Foufopoulos, Johannes, Aguirre, A Alonso, Pearl, Mary, David J. Bradley, Gary M. Tabor, Wolfe, Nathan D, Jon Epstein, Wolfe, Nathan D., Silbergeld, E., Haines, A., LeBlancq, S., Cunningham, A. A., Ashford, R. W., Rosenthal, J. P., Barthelemy, D., Bos, R., Jamaluddin, A., Lele, S., Randriamanajara, O., Patz, Jonathan A., Furu, P., Corvalan, C., Tabor, Gary M., Riach, J., Koren, H. S., Aguirre, A. Alonso, Graham, D., Thomson, M., Buck, A., Lindsay, S., Pimentel, D., Yameogo, L., Koontz, F., Dobson, A. P., Confalonieri, U. E., Zakarov, V., Butler, C., Epstein, J., Clark, G., McMichael, T., Bradley, D. J., Bradley, David J., Norris, D. E., Colwell, R., Hyatt, A. D., Else, J. G., Kilpatrick, A. Marm, Gascon, C., Rakototiana, L., Chua, K. B., Dein, J., McLean, R. G., Vittor, A. Y., Maynard, N., Chivian, E. S., Salazar-Sanchez, E., Kleinau, E. F., Amerasinghe, F. P., Pearl, M. C., Ostfeld, R. S., Field, H., Morse, S. S.   +77 more
core   +1 more source

Trained immunity: A “new” weapon in the fight against infectious diseases

Frontiers in Immunology, 2023
Innate immune cells can potentiate the response to reinfection through an innate form of immunological memory known as trained immunity. The potential of this fast-acting, nonspecific memory compared to traditional adaptive immunological memory in ...
Am Dagenais, Carlos Villalba-Guerrero, M. Olivier   +2 more
semanticscholar   +1 more source

Common Variable Immunodeficiency Non-Infectious Disease Endotypes Redefined Using Unbiased Network Clustering in Large Electronic Datasets

Frontiers in Immunology, 2018
Common variable immunodeficiency (CVID) is increasingly recognized for its association with autoimmune and inflammatory complications. Despite recent advances in immunophenotypic and genetic discovery, clinical care of CVID remains limited by our ...
J. Farmer, Mei-Sing Ong, Sara Barmettler, L. Yonker, R. Fuleihan, K. Sullivan, C. Cunningham-Rundles, J. Walter   +7 more
semanticscholar   +1 more source

Pharmacokinetic/pharmacodynamic modelling approaches in paediatric infectious diseases and immunology [PDF]

, 2014
Pharmacokinetic/pharmacodynamic (PKPD) modelling is used to describe and quantify dose-concentration-effect relationships. Within paediatric studies in infectious diseases and immunology these methods are often applied to developing guidance on ...
Hoare, RL, Germovsek, Eva, Standing, JF, Standing, Joseph F., Lewis, J, Barker, Charlotte I.S., Lewis, Joanna, Lestner, Jodi M., Hoare, Rollo L., Barker, CI, Germovsek, E, Lestner, JM   +11 more
core   +1 more source

Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses

JCI Insight, 2022
The role of immune responses to previously seen endemic coronavirus epitopes in severe acute respiratory coronavirus 2 (SARS-CoV-2) infection and disease progression has not yet been determined.
Anna L. McNaughton, Robert S. Paton, Matthew Edmans, Jonathan Youngs, Judith Wellens, Prabhjeet Phalora, Alex Fyfe, Sandra Belij-Rammerstorfer, Jai S. Bolton, Jonathan Ball, George W. Carnell, Wanwisa Dejnirattisai, Christina Dold, David W. Eyre, Philip Hopkins, Alison Howarth, Kreepa Kooblall, Hannah Klim, Susannah Leaver, Lian Ni Lee, César López-Camacho, Sheila F. Lumley, Derek C. Macallan, Alexander J. Mentzer, Nicholas M. Provine, Jeremy Ratcliff, Jose Slon-Compos, Donal Skelly, Lucas Stolle, Piyada Supasa, Nigel Temperton, Chris Walker, Beibei Wang, Duncan Wyncoll, Oxford Protective T Cell Immunology for COVID-19 (OPTIC) consortium, Scottish National Blood Transfusion Service (SNBTS) consortium, Peter Simmonds, Teresa Lambe, John Kenneth Baillie, Malcolm G. Semple, Peter J.M. Openshaw, International Severe Acute Respiratory and emerging Infection Consortium Coronavirus Clinical Characterisation Consortium (ISARIC4C) investigators, Uri Obolski, Marc Turner, Miles Carroll, Juthathip Mongkolsapaya, Gavin Screaton, Stephen H. Kennedy, Lisa Jarvis, Eleanor Barnes, Susanna Dunachie, José Lourenço, Philippa C. Matthews, Tihana Bicanic, Paul Klenerman, Sunetra Gupta, Craig P. Thompson   +56 more
doaj   +1 more source

Immunology of SARS-CoV-2 infections in children

Nature Immunology, 2022
Children and adolescents exhibit a broad range of clinical outcomes from SARS-CoV-2 infection, with the majority having minimal to mild symptoms. Additionally, some succumb to a severe hyperinflammatory post-infectious complication called multisystem ...
J. Chou, P. Thomas, A. Randolph
semanticscholar   +1 more source

Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses

JCI Insight, 2022
The Aedes aegypti mosquito transmits both dengue virus (DENV) and Zika virus (ZIKV) . Individuals in endemic areas are at risk for infection with both viruses, as well as for repeated DENV infection.
Laura K. Aisenberg, Kimberly E. Rousseau, Katherine Cascino, Guido Massaccesi, William H. Aisenberg, Wensheng Luo, Kar Muthumani, David B. Weiner, Stephen S. Whitehead, Michael A. Chattergoon, Anna P. Durbin, Andrea L. Cox   +11 more
doaj   +1 more source

Barry Bloom and the convergence of immunology, infectious disease, and public health.

Proceedings of the National Academy of Sciences of the United States of America
In early 2026, the world lost Barry Bloom, a great advocate for public health, an extraordinarily accomplished immunologist, and a science advisor who helped refocus policy on controlling infectious diseases, including neglected diseases such as leprosy.
S. Fortune, William R. Jacobs, A. Casadevall   +2 more
semanticscholar   +1 more source

Circulating microRNAs as Potential Biomarkers of Infectious Disease

Frontiers in Immunology, 2017
microRNAs (miRNAs) are a class of small non-coding endogenous RNA molecules that regulate a wide range of biological processes by post-transcriptionally regulating gene expression.
Carolina N. Correia, N. Nalpas, Kirsten E. McLoughlin, J. Browne, S. Gordon, D. MacHugh, R. Shaughnessy   +6 more
semanticscholar   +1 more source