Results 31 to 40 of about 5,981,210 (344)
JCI Insight, 2021 Hepatitis B virus–specific (HBV-specific) CD8+ T cells fail to acquire effector functions after priming in the liver, but the molecular basis for the dysfunction is poorly understood.
Keigo Kawashima +7 more
doaj +1 more source
Emerging role of macrophages in non-infectious diseases: An update.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023 In the past three decades, a huge body of evidence through various research studies conducted on animal models, has demonstrated that the macrophages are centralized of all the leukocytes involved in diseases and, particularly, their role in non ...
Hassan Yousaf +4 more
semanticscholar +1 more source
The Journal of Clinical Investigation, 2023 BACKGROUND To date, only limited data are available on the mechanisms of protection against colonization with Bordetella pertussis in humans.METHODS In this study, the cellular responses to B.
Annieck M. Diks +10 more
doaj +1 more source
The Self Model and the Conception of Biological Identity in Immunology [PDF]
, 2005 The self/non-self model, first proposed by F.M. Burnet, has dominated immunology for sixty years now. According to this model, any foreign element will trigger an immune reaction in an organism, whereas endogenous elements will not, in normal ...
Pradeu, Thomas +5 more
core +1 more source
Germline IgM predicts T cell immunity to Pneumocystis
JCI Insight, 2022 Pneumocystis is the most common fungal pulmonary infection in children under the age of 5 years. In children with primary immunodeficiency, Pneumocystis often presents at 3–6 months of age, a time period that coincides with the nadir of maternal IgG and ...
Kristin Noell +6 more
doaj +1 more source
Immunology of COVID‐19 and disease‐modifying therapies: The good, the bad and the unknown
European Journal of Neurology, 2020 The outbreak of the SARS‐CoV‐2 pandemic, caused by a previously unknown infectious agent, posed unprecedented challenges to healthcare systems and unmasked their vulnerability and limitations worldwide.
Tobias Zrzavy +3 more
semanticscholar +1 more source
Detailed monitoring of a small but recovering population reveals sublethal effects of disease and unexpected interactions with supplemental feeding [PDF]
, 2015 Infectious diseases are widely recognized to have substantial impact on wildlife populations. These impacts are sometimes exacerbated in small endangered populations, and therefore, the success of conservation reintroductions to aid the recovery of such ...
Richards, Heather +17 more
core +1 more source
Features and protective efficacy of human mAbs targeting Mycobacterium tuberculosis arabinomannan
JCI Insight, 2023 A better understanding of the epitopes most relevant for antibody-mediated protection against tuberculosis (TB) remains a major knowledge gap. We have shown that human polyclonal IgG against the Mycobacterium tuberculosis (M. tuberculosis) surface glycan
Yanyan Liu +8 more
doaj +1 more source
Human monkeypox: epidemiology, transmission, pathogenesis, immunology, diagnosis and therapeutics
Molecular and Cellular Biochemistry, 2023 “Zoonoses” describe diseases that may be acquired by humans from animals. Due to the constant contact between humans and other animals, many infectious diseases are disseminated.
Manish Thakur, P. Das, R. Sobti, T. Kaur
semanticscholar +1 more source
Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis
The Journal of Clinical Investigation, 2023 Recognition of pathogen-associated molecular patterns can trigger the inositol-requiring enzyme 1 α (IRE1α) arm of the endoplasmic reticulum (ER) stress response in innate immune cells.
Deepika Awasthi +18 more
doaj +1 more source