Results 41 to 50 of about 5,981,210 (344)
Q fever immunology: the quest for a safe and effective vaccine
npj Vaccines, 2023 Q fever is an infectious zoonotic disease, caused by the Gram-negative bacterium Coxiella burnetii . Transmission occurs from livestock to humans through inhalation of a survival form of the bacterium, the Small Cell Variant, often via handling of animal
Gayathri Sam +3 more
semanticscholar +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Household structure and infectious disease transmission [PDF]
, 2009 One of the central tenets of modern infectious disease epidemiology is that an understanding of heterogeneities, both in host demography and transmission, allows control to be efficiently optimized.
Keeling, M J +3 more
core +1 more source
npj VaccinesChlamydia trachomatis (C.t.) is globally the most common sexually transmitted bacterium with an estimated 131 million new cases occurring every year. There is no licenced vaccine against C.t.
Nina Dieu Nhien Tran Nguyen +7 more
doaj +1 more source
JCI Insight, 2021 Prime-boost immunization strategies are required to control the global tuberculosis (TB) pandemic, which claims approximately 3 lives every minute. Here, we have generated an immunogenic complex against Mycobacterium tuberculosis (M.tb), consisting of ...
Santosh Kumar +8 more
doaj +1 more source
NLRP12‐PANoptosome in haemolytic, infectious and inflammatory diseases
Clinical and Translational Medicine, 2023 Invading pathogens and homeostatic perturbations activate the innate immune system as the body’s first line of defense. Innate immunity is driven by pattern recognition receptors (PRRs),1 which can activate by: 1) acting as direct receptors that bind ...
Rebecca E. Tweedell, T. Kanneganti
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
A space-time conditional intensity model for infectious disease occurence [PDF]
, 2010 A novel point process model continuous in space-time is proposed for infectious disease data. Modelling is based on the conditional intensity function (CIF) and extends an additive-multiplicative CIF model previously proposed for discrete space epidemic ...
Höhle, Michael +5 more
core +1 more source
Acknowledgment to Reviewers of Tropical Medicine and Infectious Disease in 2020
, 2021 Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Tropical Medicine and Infectious Disease maintains its standards for the high quality of its published papers [...
Tropical Medicine Infectious Disease Editorial Office Tropical Medicine Infectious Disease Editorial Office
core +2 more sources
Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection
JCI Insight, 2021 Superficial cutaneous Staphylococcus aureus (S. aureus) infection in humans can lead to soft tissue infection, an important cause of morbidity and mortality.
Juan-Manuel Leyva-Castillo +10 more
doaj +1 more source