Results 101 to 110 of about 106,431 (292)
, 2019 Figure S1. CK values measured over time for patient 1 (circle), patient 2 (square) and patient 3 (triangle). Closed symbols represent CK values taken before secondary immunomodulation; all open symbols represent measurements taken after immunomodulation.
A. Ploeg (6500627) +8 more
core +1 more source
Advanced Science, EarlyView.A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal +5 more
wiley +1 more source
Immunomodulation, Part V: Probiotics
, 2007 ACCORDING TO 2003 CENTERS for Disease Control and Prevention statistics, bacterial sepsis of the newborn is the eighth leading cause of death among neonates of all races and both sexes in the U.S., with a mortality rate of 18.9 per 100,000 live births ...
Susan Givens Bell
core +1 more source
Advanced Science, EarlyView.Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang +7 more
wiley +1 more source
Pharmacological Immunomodulation Therapies In Cancer Treatment
Cancer is presenting a significant challenge to healthcare systems and prompting extensive research into novel treatment strategies. Traditional cancer therapies like surgery, radiation and chemotherapy often face limitations including nonspecificity ...
Nuraly, Dilara
core
Advanced Science, EarlyView.Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou +10 more
wiley +1 more source
Advanced Science, EarlyView.A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang +5 more
wiley +1 more source
Advanced Science, EarlyView.The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang +12 more
wiley +1 more source
Advanced Science, EarlyView.Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong +8 more
wiley +1 more source
Stem Cell Research & TherapyBackground Human platelet lysate (hPL) has emerged as a promising serum substitute to enhance the self-renewal and multipotency of human mesenchymal stem cells (MSCs).
Ping Du +7 more
doaj +1 more source