Results 11 to 20 of about 127,738 (207)

NATURALLY OCCURRING AND SYNTHETIC IMMUNOMODULATORS WITH DIFFERENT BIOLOGICAL ACTIVITIES: LITERATURE SURVEY AND HISTORICAL INSIGHT [PDF]

open access: yesAl-Azhar Journal of Pharmaceutical Sciences, 2021
An immunomodulator is a substance that stimulates or suppresses the immune system and may help the body fight cancer. The aim of this review is to highlight results of research done on immunomodulators of natural or synthetic origin showing different ...
Mohamed El-Zahabi
doaj   +1 more source

Immunomodulatory Drugs in Acute Myeloid Leukemia Treatment [PDF]

open access: yesCancers, 2020
Francesco Albano   +2 more
exaly   +2 more sources

Immunomodulatory and Antioxidant Drugs in Glaucoma Treatment

open access: yesPharmaceuticals, 2023
Glaucoma, a group of diseases characterized by progressive retinal ganglion cell loss, cupping of the optic disc, and a typical pattern of visual field defects, is a leading cause of severe visual impairment and blindness worldwide.
Francesco Buonfiglio   +2 more
doaj   +1 more source

Antifungal and Immunomodulatory Ingredients from Traditional Chinese Medicine

open access: yesAntibiotics, 2022
Fungal infections have become a growing public health challenge due to the clinical transmission of pathogenic fungi. The currently available antifungal drugs leave very limited choices for clinical physicians to deal with such situation, not to mention ...
Hua Zhong, Lei Han, Ren-Yi Lu, Yan Wang
doaj   +1 more source

Research Progress on Immunoregulation of Chemotherapeutic Agents

open access: yesZhongliu Fangzhi Yanjiu, 2022
Chemotherapeutic drugs are the mainstay of treatment on mid-advanced tumors. In recent years, more and more studies have shown that chemotherapeutic drugs also have immunomodulatory effects.
LIU Zhenghao, YANG Chunguang, HU Zhiquan
doaj   +1 more source

Potential therapies against SARS-CoV-2 virus evaluated in large-scale clinical trials [PDF]

open access: yesRomanian Journal of Pharmaceutical Practice, 2022
COVID-19 is a viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pathogenesis of SARS-CoV-2 infection in humans manifests as mild symptoms to severe respiratory failure.
Alin-Viorel Focsa   +4 more
doaj   +1 more source

RXR Agonists Enhance Lenalidomide Anti-Myeloma Activity and T Cell Functions while Retaining Glucose-Lowering Effect

open access: yesCells, 2023
Retinoid X receptor (RXR) heterodimerizes with the PPAR nuclear hormone receptor and regulates its downstream events. We investigated the effects of RXR agonists (LG100754, bexarotene, AGN194204, and LG101506) on lenalidomide’s anti-myeloma activity, T ...
Jian Wu   +4 more
doaj   +1 more source

Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation

open access: yesHaematologica, 2018
The immunomodulatory drugs, lenalidomide and pomalidomide yield high response rates in multiple myeloma patients, but are associated with a high rate of thrombocytopenia and increased risk of secondary hematologic malignancies.
Ailing Liu   +10 more
doaj   +1 more source

Pomalidomide for Treatment of Relapsed and Refractory Multiple Myeloma

open access: yesКлиническая онкогематология, 2015
Pomalidomide is a third-generation immunomodulatory drug recommended for patients with multiple myeloma refractory to lenalidomide and bortezomib. The safety profile is optimized for application in patients with intensive and continuous anti-tumor ...
Sergei Vyacheslavovich Semochkin
doaj   +1 more source

Immunomodulatory Drugs Alter the Metabolism and the Extracellular Release of Soluble Mediators by Normal Monocytes

open access: yesMolecules, 2020
Immunomodulatory drugs (IMiDs) are used in the treatment of hematological malignancies, especially multiple myeloma. IMiDs have direct anticancer effects but also indirect effects via cancer-supporting stromal cells.
Ida Marie Rundgren   +4 more
doaj   +1 more source

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