Results 31 to 40 of about 1,214,228 (245)

Drugs influencing orthodontic tooth movement: An overall review

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Orthodontic treatment is based on the premise that when force is delivered to a tooth and thereby transmitted to the adjacent investing tissues, certain mechanical, chemical, and cellular events take place within these tissues, which allow for structural
Kamatchi Diravidamani   +2 more
doaj   +1 more source

Revealing the microbial composition changes and relationship with Fusarium caused by rot disease in the Crocus sativus L.

open access: yesAnnals of Microbiology
Purpose Rot disease caused by Fusarium poses a formidable threat to the growth of saffron (Crocus sativus L.), resulting in substantial damage to both yield and quality.
Jia Song   +6 more
doaj   +1 more source

Genome-wide identification and characterization of WOX gene family in saffron (Crocus sativus L.) and their roles in stress response, development and callus formation

open access: yesFrontiers in Plant Science
IntroductionThe shoot apical meristem (SAM) of saffron (Crocus sativus L.) plays a critical role in floral transition and development. WUSCHEL-related homeobox (WOX) genes are key regulators of stem cell activity and SAM size across diverse species ...
Yuanyuan Tao   +23 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

An efficient method for tissue-specific protoplast isolation suitable for single-cell RNA sequencing and transient gene expression analysis in saffron (Crocus sativus L.)

open access: yesBMC Biotechnology
Background Protoplasts have been widely utilized in tissue culture, single-cell RNA sequencing, and transient gene expression analyses. However, the primary challenge in their preparation lies in the efficient removal of rigid cell walls to obtain high ...
Xiaoyuan Xi   +5 more
doaj   +1 more source

EFFECT OF STIMFORTE UPON MURINE MONONUCLEAR LEUKOCYTES AND LYMPHOID ORGANS DURING CYCLOPHOSPHAN TREATMENT

open access: yesМедицинская иммунология, 2014
.  We  studied  effects  of  Stimforte,  an  immunomodulatory  drug  of  animal  origin,  upon mononuclear leukocytes (MLs) and morphology of lymphoid organs in the course of cyclophosphan-induced immunosuppression.
D. G. Maldov   +9 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Effects of saffron-grape intercropping on saffron flower number and rhizosphere microbial community

open access: yesBMC Microbiology
Background Saffron (Crocus sativus L.) is a valuable herb. With the increasing demand for saffron, people are starting to focus on how to increase its yields.
Yuanyuan Tao   +5 more
doaj   +1 more source

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