Results 81 to 90 of about 19,820 (199)

Pathogenesis of Tuberculosis: Interplay Between Host Antituberculosis Immunity and Immune Evasion Strategies of Mycobacterium Tuberculosis

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang   +3 more
wiley   +1 more source

MIF‐MAPMS: Enhancing identification of myelin autoantigenic peptides in multiple sclerosis through multimodal information fusion

open access: yesProtein Science, Volume 35, Issue 8, August 2026.
Abstract Multiple sclerosis (MS) arises from an autoimmune response in which the immune system erroneously targets myelin autoantigens within the central nervous system, leading to myelin degradation and subsequent neurological dysfunction. Identifying myelin autoantigenic peptides (MAPs) is therefore critical for understanding MS pathogenesis and ...
Watshara Shoombuatong   +4 more
wiley   +1 more source

Involvement of Hookworm Co-Infection in the Pathogenesis and Progression of Podoconiosis: Possible Immunological Mechanism

open access: yesTropical Medicine and Infectious Disease, 2018
Podoconiosis is an endemic, non-infectious, geochemical and non-filarial inflammatory cause of tropical elephantiasis. The immunology of podoconiosis is not yet expressly understood.
Damilare O. Famakinde   +1 more
doaj   +1 more source

Allergen‐specific immunotherapy guided by skin prick testing in a Canadian shepherd dog with atopic dermatitis

open access: yesVeterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract This case report describes the successful use of allergen‐specific immunotherapy guided by skin prick testing in a Canadian shepherd dog with atopic dermatitis. The dog presented severe pruritus, hypotrichosis, erythema and generalised scaling. Hyperpigmentation and lichenification were observed on the hindlimbs, thoracic and lateral abdominal
Aléxia Vitória Rocha Dutra   +2 more
wiley   +1 more source

Immunopathogenic features of hemorrhagic fever with renal syndrome as criteria for early immunodiagnostics

open access: yesRUDN Journal of Medicine
Relevance. Hemorrhagic fever with renal syndrome (HFRS) is a natural focal viral infection with a high probability of severe course, the possibility of death, a long recovery period after infection, low effectiveness of therapy and vaccine prevention. In
Michail F. Ivanov   +3 more
doaj   +1 more source

Oral lichenoid lesions in CTLA‐4 haploinsufficiency: Targeting IFN‐γ‐driven mucosal immunopathology

open access: yes
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chen Wang   +11 more
wiley   +1 more source

Immunohistochemical Evaluation of TLR‐4, HSP‐70 and Caspase‐3 Expressions in Lesional Areas of Ecthyma Disease

open access: yesVeterinary Dermatology, Volume 37, Issue 4, Page 549-556, August 2026.
Background: Contagious ecthyma (Orf) is a highly contagious, economically significant disease affecting sheep, goats and wild small ruminants, caused by the resilient Orf virus (ORFV). It produces thick, crusted lesions around the mouth and nostrils, especially in animals aged 3–4 months, sometimes causing near 100% mortality in immunocompromised young
Emine Nur Dincer, Ozlem Ozmen
wiley   +1 more source

Microarray Gene Expression Analysis of Lesional Skin in Canine Vesicular Cutaneous Lupus Erythematosus (VCLE)

open access: yesVeterinary Dermatology, Volume 37, Issue 4, Page 478-487, August 2026.
Background: Vesicular cutaneous lupus erythematosus (VCLE) is a rare autoimmune disease in dogs and is considered the canine counterpart of human subacute cutaneous lupus erythematosus (SCLE). However, the molecular mechanisms underlying VCLE remain incompletely defined.
Treasa Clifford   +5 more
wiley   +1 more source

IL‐33/ST2 Signaling Sustains Hepato‐Intestinal Homeostasis by Orchestrating Vascular Surveillance and Immune Regulatory Circuits During Experimental Trypanosoma cruzi Infection

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Impairment of hepato‐intestinal homeostasis triggered by ST2 deficiency during T. cruzi infection. Within the splenic compartment, immune dysregulation is marked by a robust pro‐inflammatory polarization of the T‐cell landscape. In the liver, ST2 deficiency is associated with hepatocellular injury, increased parasite burden, and hyperalbuminemia ...
Marcelo Eduardo Cardozo   +22 more
wiley   +1 more source

The Synthetic Melanocortin Agonist NDP‐MSH Ameliorates THSD7A‐Associated Membranous Nephropathy in an Active Immunization Mouse Model

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Active immunization with recombinant THSD7A in mice induces autoreactive B cell activation and differentiation into CD138+ antibody‐secreting cells, leading to the production of anti‐THSD7A autoantibodies, glomerular immune injury and proteinuria, characteristic of membranous nephropathy. NDP‐MSH treatment modulates the MITF/IRF4 axis in primed B cells,
Mingzhuo Zhang   +4 more
wiley   +1 more source

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