Results 151 to 160 of about 44,987 (258)

Restoring immune balance with low‐dose interleukin‐2 in a patient with anti‐synthetase syndrome and recurrent infections: A case report

open access: yesRheumatology &Autoimmunity, EarlyView.
This figure summarizes the clinical course and immune reconstitution in a patient with anti‐synthetase syndrome (ASyS) and recurrent refractory infections. Left panel: conventional immunosuppression is associated with marked Treg deficiency and persistent infections. Middle panel: intervention with subcutaneous low‐dose interleukin (IL)−2. Right panel:
Tian Gao   +8 more
wiley   +1 more source

Intersection of systemic lupus erythematosus and autoimmune thyroid disease: Shared pathophysiology, epidemiology, diagnosis, and management

open access: yesRheumatology &Autoimmunity, EarlyView.
A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa   +3 more
wiley   +1 more source

Angiogenesis‐associated immune genes as prognostic markers and predictors of immunotherapy response in pancreatic ductal adenocarcinoma

open access: yesVIEW, EarlyView.
Pancreatic ductal adenocarcinoma exhibits marked angiogenic and immune heterogeneity. We identified 28 angiogenesis‐associated immune genes and developed a seven‐gene AIGScore model comprising FGF2, ADGRB3, MMP2, TYMP, VASH1, VEGFD, and ITGAV. A high AIGScore was associated with poor survival, an immunosuppressive tumor microenvironment, and reduced ...
Qing Chang   +4 more
wiley   +1 more source

Passenger variants as pan-clonal markers of pediatric AML: Implications for molecular MRD. [PDF]

open access: yesHemasphere
Shiloh R   +20 more
europepmc   +1 more source

Biomarkers Predictive of Immunotherapy Efficacy in Head and Neck Squamous Cell Carcinoma: Current Insights and Future Perspectives

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT With the approval of immunotherapies by regulatory bodies, head and neck squamous cell carcinoma (HNSCC) treatment has been revolutionized, and anti‐programmed cell death‐1 (anti‐PD‐1) agents are now the standard for platinum‐resistant recurrent/metastatic HNSCC.
Xiao‐Tong Yan   +2 more
wiley   +1 more source

Immunophenotypic, Cytogenetic, and Molecular Characterization of NUP98-Rearranged Pediatric Myeloid Neoplasms. [PDF]

open access: yesMod Pathol
Khanlari M   +11 more
europepmc   +1 more source

Chronic Pruritic Papular Eruption in an Elderly Man

open access: yes
JEADV Clinical Practice, EarlyView.
Filipe Monteiro   +6 more
wiley   +1 more source

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