Results 191 to 200 of about 44,987 (258)

Thrombosis-Associated Risk Factors in Pediatrics and Adults Treated with Asparaginase-Containing Chemotherapy for ALL: A Systematic Review and Meta-Analysis. [PDF]

Curr Oncol
Seki JT, Atenafu EG, Sibai H.
europepmc   +1 more source

INHBB Promotes Colorectal Cancer Progression by Inducing CD8+ T Cell Exhaustion via the ACVR2B‐SMAD Signaling Axis

Cancer Science, EarlyView.
INHBB secreted by colorectal cancer cells activates ACVR2B‐SMAD signaling to induce CD8+ T‐cell exhaustion and drive tumor progression. SB431542 blocks this oncogenic immune‐suppressive axis. ABSTRACT To investigate the expression pattern, biological functions and regulatory mechanisms of inhibin beta B (INHBB) in colorectal cancer (CRC), and to ...
Guanghui Liu, Yuanhua Liu, Hongchao Zhao, Junfeng Sun, Hongwei Yang, Qingqing Ding   +5 more
wiley   +1 more source

Drug reaction with eosinophilia and systemic symptoms or peripheral T-cell lymphoma? That is the question. [PDF]

Postepy Dermatol Alergol
Grabarczyk M, Swoboda R, Michalak K, Ponikiewska D, Smyk J, Krawczyk-Kuliś M, Giebel S, Pastuszczak M, Kamińska-Winciorek G.   +8 more
europepmc   +1 more source

Flow cytometric identification of plasmacytoid dendritic cells in acute myeloid leukaemia: Challenges and practical considerations

British Journal of Haematology, EarlyView.
Mariana S. Vieira, Pietro B. Belmonte, Natália A. Marcondes, Raquel Q. Vidal, Flavo B. Fernandes, Liane N. Rotta   +5 more
wiley   +1 more source

A20 Inhibits IFN‐γ Signaling in Hepatocellular Carcinoma Cells by Binding to STAT1, Compromising Anti‐Tumor Immunity

Cancer Science, EarlyView.
A20 suppresses IFN‐γ signaling in HCC cells by binding to STAT1 through its ZnF7 domain, thereby reducing CXCL9, CXCL10, and HLA‐ABC expression, ultimately impairing CD8+ T‐cell‐mediated anti‐tumor immunity. ABSTRACT Immune checkpoint blockade (ICB) has demonstrated efficacy in clinical cancer therapy; however, a significant proportion of cancer ...
Yanlei Dong, Jing Yi, Ruoxuan Yang, Yingyue Wang, Zelong Ma, Hong Yuan, Meichen Song, Ying Xiao, Chun Guo, Jianing Wang, Xiaoyan Wang, Faliang Zhu, Lining Zhang, Yuchen Fan, Yongyu Shi   +14 more
wiley   +1 more source

Synchronous Early Gastric Adenocarcinoma and Cervical Carcinoma of Unknown Primary with Metachronous Hepatocellular Carcinoma: A Case Report. [PDF]

Onco Targets Ther
Li Y, Zhao H, Fu C, Gong L, Li D, Lin X, Ran B.   +6 more
europepmc   +1 more source

Distinct Clinical Features of Multiple Myeloma With t(11;14): A Post Hoc Analysis of JSH‐MM‐15 Study

Cancer Science, EarlyView.
t(11;14)‐positive MM is a clinically distinct subgroup characterized by intermediate prognostic risk, modest response depth, and treatment‐dependent outcomes. ABSTRACT t(11;14) (q13;q32) occurs in approximately 15%–25% of multiple myeloma (MM) cases and has traditionally been regarded as a standard cytogenetic risk factor.
Taku Tsukamoto, Yuji Shimura, Shinsuke Mizutani, Takahiro Fujino, Haruya Okamoto, Mitsuhiro Itagaki, Hiroshi Handa, Takayuki Shimizu, Morio Sawamura, Tadao Ishida, Satoru Kosugi, Shuichi Ota, Makoto Yoshimitsu, Yutaka Shimazu, Isamu Sugiura, Hirohiko Shibayama, Shin‐ichi Fuchida, Hiroyuki Takamatsu, Akiko M. Saito, Hitoshi Kiyoi, Koichi Akashi, Itaru Matsumura, Akifumi Takaori‐Kondo, Junya Kuroda, Shinsuke Iida   +24 more
wiley   +1 more source

Genotype-immunophenotype relationships in NPM1-mutated AML clonal evolution uncovered by single-cell multiomic analysis.

Blood
Drucker M, Lee D, Bowman M, Zhang X, Kain BN, Nicolet D, Bandopadhyay R, Singh V, Wang Z, Stone RM, Saygin C, Mrózek K, Carroll AJ, Starczynowski DT, Levine RL, Byrd JC, Salomonis N, Skuli SJ, Grimes HL, Eisfeld AK, Bowman RL, Miles LA.   +21 more
europepmc   +1 more source