Results 11 to 20 of about 39,466 (197)

Application and interpretation of immunophenotyping data in safety and risk assessment [PDF]

open access: yesFrontiers in Toxicology
The use of immunophenotyping during immunotoxicity investigations was first popularized in the 1980 s and has since become more integrated into diagnostic and non-clinical assessments.
Victor J. Johnson   +7 more
doaj   +2 more sources

Carboxypeptidase A3—A Key Component of the Protease Phenotype of Mast Cells

open access: yesCells, 2022
Carboxypeptidase A3 (CPA3) is a specific mast cell (MC) protease with variable expression. This protease is one of the preformed components of the secretome.
Dmitri Atiakshin   +5 more
doaj   +1 more source

Mast Cells in Regeneration of the Skin in Burn Wound with Special Emphasis on Molecular Hydrogen Effect

open access: yesPharmaceuticals, 2023
The mechanisms of regeneration for the fibrous component of the connective tissue of the dermis are still insufficiently studied. The aim of this study was to evaluate the effectiveness of the use of molecular hydrogen on the local therapy of a II degree
Dmitri Atiakshin   +8 more
doaj   +1 more source

Mast Cells as a Potential Target of Molecular Hydrogen in Regulating the Local Tissue Microenvironment

open access: yesPharmaceuticals, 2023
Knowledge of the biological effects of molecular hydrogen (H2), hydrogen gas, is constantly advancing, giving a reason for the optimism in several healthcare practitioners regarding the management of multiple diseases, including socially significant ones
Dmitri Atiakshin   +8 more
doaj   +1 more source

The Use of CD200 in the Differential Diagnosis of B-Cell Lymphoproliferative Disorders

open access: yesBritish Journal of Biomedical Science, 2023
Background: B-Cell Lymphoproliferative Disorders (B-LPDs) are a group of heterogenous disorders characterised by the accumulation of B-cells in peripheral blood, bone marrow, lymph nodes and spleen.
Hanaan Kareem Al-Zubaidi   +1 more
doaj   +1 more source

Highly Sensitive and Accurate Assessment of Minimal Residual Disease in Chronic Lymphocytic Leukemia Using the Novel CD160-ROR1 Assay

open access: yesFrontiers in Oncology, 2020
Undetectable minimal residual disease (MRD) in Chronic Lymphocytic Leukemia (CLL) has a favorable prognostic outcome compared with MRD that can be detected.
Timothy W. Farren   +4 more
doaj   +1 more source

Low Dose Radiation Therapy Induces Long-Lasting Reduction of Pain and Immune Modulations in the Peripheral Blood – Interim Analysis of the IMMO-LDRT01 Trial

open access: yesFrontiers in Immunology, 2021
The treatment of chronic inflammatory and degenerative diseases by low dose radiation therapy (LDRT) is promising especially for patients who were refractory for classical therapies.
Anna-Jasmina Donaubauer   +16 more
doaj   +1 more source

An Unusual Case of Primary Plasma Cell Leukaemia Mimicking Acute Leukaemia: A Case Report and Review of Literature [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Plasma Cell Leukaemia (PCL) is rare and an aggressive disease accounting for only 2-3% of all plasma cell dyscrasias. Diagnosis is made when there are more than 2x109 /L plasma cells in the peripheral blood or monoclonal plasmacytosis more than 20% of
Abha Singla, Monica Gupta
doaj   +1 more source

From Conventional to Precision Therapy in Canine Mammary Cancer: A Comprehensive Review

open access: yesFrontiers in Veterinary Science, 2021
Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs. Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the elective treatment, additional targeted and non-targeted therapies could offer benefits
Guillermo Valdivia   +7 more
doaj   +1 more source

Highly Multiplexed Phenotyping of Immunoregulatory Proteins in the Tumor Microenvironment by CODEX Tissue Imaging

open access: yesFrontiers in Immunology, 2021
Immunotherapies are revolutionizing cancer treatment by boosting the natural ability of the immune system. In addition to antibodies against traditional checkpoint molecules or their ligands (i.e., CTLA-4, PD-1, and PD-L1), therapies targeting molecules ...
Darci Phillips   +8 more
doaj   +1 more source

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