Results 261 to 270 of about 63,836 (336)

Telotristat ethyl affects tumour‐fibroblast crosstalk in small intestinal neuroendocrine tumours

Journal of Neuroendocrinology, EarlyView.
Abstract Small intestinal neuroendocrine tumours (SI‐NETs) are associated with mesenteric fibrosis, which causes significant morbidity and mortality. Telotristat ethyl was developed to treat carcinoid syndrome in SI‐NET patients. Recent studies indicated telotristat ethyl could have anti‐tumour activity; however, the mechanism remains unclear.
Harry Hodgetts, Maria Castanho Martins, Luohai Chen, Andrew R. Hall, Tu Vinh Luong, Dalvinder Mandair, Martyn Caplin, Krista Rombouts   +7 more
wiley   +1 more source

Novel Compound Heterozygous Mutations in HOIP Result in Autoinflammation and Immunodeficiency. [PDF]

J Clin Immunol
Wang L, Xiao J, Gan R, Tang X, Wu J.
europepmc   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Integrative immune analysis in patients with leprosy reveals host factors associated with mycobacterial control. [PDF]

EBioMedicine
van Hooij A, van Meijgaarden KE, Khatun M, Soren S, Walburg K, Alam K, Chowdhury AS, van Hees CLM, Richardus JH, Geluk A.   +9 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Apoptosis kinetics of purified and PBMC‐associated lymphocytes after photopheresis‐like 8‐methoxypsolaren/UVA treatment

Photochemistry and Photobiology, EarlyView.
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde, Imilla Casado Hernandez, Yandy Marx Castillo‐Aleman, Gisela Maria Suarez‐Formigo, Amar Riaz, Antonio Alfonso Bencomo‐Hernandez, Yendry Ventura‐Carmenate   +6 more
wiley   +1 more source

CD103-Negative Hairy Cell Leukemia: A Case Report From University Teaching Hospital, Zambia. [PDF]

Case Rep Med
Kaweme NM, Butress SMN, Akekelwa I, Kowa SF, Mantina HM, Mwandama CK.   +5 more
europepmc   +1 more source

Spatially and Clonally Multiple B‐/Plasma Cell Proliferations in T Follicular Helper Cell Lymphoma: A Case Report

Pathology International, EarlyView.
A patient with TFHL developed spatiotemporally, pathologically, and clonally multiple B/PC‐Ps. The cellular composition of the neoplastic TFH cells and monoclonal B/PC‐Ps significantly differed by time and location; the pleural effusion was T‐cell‐predominant, whereas cutaneous lesions predominantly consisted of monoclonal B/PC‐Ps, which obscured TFHL.
Yuka Yokota, Naoki Oishi, Kazunari Kasai, Masataka Kawai, Ippei Tahara, Tomohiro Inoue, Yuma Sakamoto, Megumi Koshiish‐Yamada, Keita Kirito, Tetsuo Kondo   +9 more
wiley   +1 more source

Dose and Duration of Upfront Steroid Administration Have no Prognostic Impact in Dogs With Multicentric Diffuse Large B‐Cell Lymphoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Steroids provide rapid clinical improvement in dogs with multicentric diffuse large B‐cell lymphoma (DLBCL). However, their use before chemotherapy can induce chemoresistance and compromise diagnostic yield due to increased apoptotic cells.
Ilaria Maga, Silvia Sabattini, Valeria Martini, Fulvio Riondato, Luca Aresu, Laura Marconato   +5 more
wiley   +1 more source

<i>SRSF2</i> mutations in CCUS, MDS and AML: a cross-entity study. [PDF]

Blood Neoplasia
Huber S, Ochmann S, Hutter S, Ecker V, Meggendorfer M, Hoermann G, Haferlach T, Haferlach C, Summerer I.   +8 more
europepmc   +1 more source