Phenotypic Profiling of Immune Cells and Their Mediators in Chronic Obstructive Pulmonary Disease
Background: Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder and has been proposed to have an imbalance between pro-inflammatory and anti-inflammatory factors. Methods: This study was conducted on 41 participants {18 COPD patients
Meghashree Sampath +6 more
doaj +1 more source
Assessment of local tissue responses to subcutaneous implantation of Polyetheretherketone and Polymethyl methacrylate-based materials [PDF]
Background/Aim: In surgical dentistry, maxillofacial surgery and traumatology, bone tissue regeneration is one of the most pressing challenges.
Demyashkin Grigory +7 more
doaj +1 more source
Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy. [PDF]
The success of immunotherapy has led to a myriad of clinical trials accompanied by efforts to gain mechanistic insight and identify predictive signatures for personalization.
Amir, El-Ad D +13 more
core +3 more sources
Dissecting the functional diversity of T cells is critical in elucidating mechanisms and in developing therapies for various diseases. Here, we designed a 31‐parameter (29‐color) panel to enable the characterization of T‐cell subsets and ...
Song-Rong Wang +6 more
semanticscholar +1 more source
Hepatosplenic T Cell Lymphoma in an Immunocompetent Female Diagnosed using Flow Cytometry: A Rare Clinical Entity [PDF]
Hepatosplenic T-cell lymphoma is a rare haematopoietic malignancy that comprises less than 1% of Non-Hodgkin lymphomas. We are reporting a case of a 26-year-old female, who presented with pallor, weight loss, jaundice, pancytopenia and ...
Pranav Dorwal +5 more
doaj +1 more source
No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Burmeister, Thomas +4 more
core +2 more sources
An Unusual Case of Primary Plasma Cell Leukaemia Mimicking Acute Leukaemia: A Case Report and Review of Literature [PDF]
Plasma Cell Leukaemia (PCL) is rare and an aggressive disease accounting for only 2-3% of all plasma cell dyscrasias. Diagnosis is made when there are more than 2x109 /L plasma cells in the peripheral blood or monoclonal plasmacytosis more than 20% of
Abha Singla, Monica Gupta
doaj +1 more source
Only few studies exist on the phenotype distribution of peripheral blood lymphocytes concerning persistent oral HPV infection. T-lymphocyte subsets were phenotyped in women who had persistent genital or oral HPV16 infection, using HPV-negative women as a
Helmi Suominen +6 more
doaj +1 more source
Gene rearrangements in bone marrow cells of patients with acute myelogenous leukemia [PDF]
At diagnosis, clonal gene rearrangement probes {[}retinoic acid receptor (RAR)-alpha, major breakpoint cluster region (M-bcr), immunoglobulin (Ig)-JH, T cell receptor (TcR)-beta, myeloid lymphoid leukemia (MLL) or cytokine genes (GM-CSF, G-CSF, IL-3 ...
Braun, S. +5 more
core +1 more source
Multi-batch cytometry data integration for optimal immunophenotyping
We describe the integration of multi-batch cytometry datasets (iMUBAC), a flexible, robust, and scalable computational framework for unsupervised cell-type identification across multiple batches of high-dimensional cytometry datasets.
Masato Ogishi +20 more
semanticscholar +1 more source

