Results 21 to 30 of about 66,402 (234)

Evaluation of fixed-panel, multicolour ClearLLab 10C at an academic flow cytometry laboratory in Johannesburg, South Africa

African Journal of Laboratory Medicine, 2022
Background: Flow cytometric immunophenotyping is well established for the diagnosis of haematological neoplasms. New commercially available systems offer fixed, pre-aliquoted multi-parameter analysis to simplify sample preparation and standardise data ...
Deborah K. Glencross, Leanne Swart, Melanie Pretorius, Denise Lawrie   +3 more
doaj   +1 more source

Pre-B-cell acute lymphoblastic leukemia with bulk extramedullary disease and chromosome 22 (EWSR1) rearrangement masquerading as Ewing sarcoma [PDF]

, 2010
We report a 2-year-old female with a subcutaneous tumor who was initially misdiagnosed as suffering from Ewing sarcoma with a positive EWSR1 rearrangement and EWS/FLI1 transcript.
Jakovljević, Gordana, Kardum-Skelin, Ika, Krušlin, Božo, Mrsić-Davidović, Sanja, Nakić, Melita, Rogošić, Srđan, Zadro, Renata   +6 more
core   +1 more source

Harnessing the anti-inflammatory potential of Lamiaceae family hydrolates: A study of Satureja montana and Origanum vulgare in burn wound management [PDF]

Scripta Medica
Background/Aim: The management of severe thermal injuries is a significant clinical challenge, often leading to protracted inflammation, impaired tissue regeneration and increased susceptibility to infection, a situation exacerbated by growing ...
Parshenkov Mikhail, Tokov Alibek, Kuzminov Boris, Sataieva Tatiana, Popov Sergey, Tarasov Vadim, Tuktarova Amira, Demyashkin Grigory   +7 more
doaj   +1 more source

Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection

Frontiers in Immunology, 2022
BackgroundIdentifying immune processes required for liver-stage sterilizing immunity to malaria remains an open problem. The IMRAS trial comprised 5x immunizations with radiation-attenuated sporozoites resulting in 55% protection from subsequent ...
Fergal J. Duffy, Nina Hertoghs, Ying Du, Maxwell L. Neal, Damian Oyong, Suzanne McDermott, Nana Minkah, Jason Carnes, Katharine V. Schwedhelm, M. Juliana McElrath, Stephen C. De Rosa, Evan Newell, John D. Aitchison, Ken Stuart   +13 more
doaj   +1 more source

Immunophenotyping to improve the mechanistic understanding of idiosyncratic drug-induced liver injury: clinical implications and future directions

Exploration of Digestive Diseases, 2023
The late event onset of a fraction of idiosyncratic drug-induced liver injury (DILI) cases and the link observed by genome-wide association studies (GWASs) of certain human leucocyte antigen (HLA) alleles with DILI due to specific drugs support the ...
Alejandro Cueto-Sánchez, Daniel E. Di Zeo-Sánchez, Antonio Segovia-Zafra, Gonzalo Matilla-Cabello, Ana Bodoque-García, María Isabel Lucena, Marina Villanueva-Paz   +6 more
doaj   +1 more source

Immunophenotyping of Tumours [PDF]

Medical Journal Armed Forces India, 2008
Immunophenotyping has added a new dimension to improve the diagnostic accuracy of malignant diseases. The emphasis is on its usefulness in planning and institution of specific therapy besides helping in prognostication.The study included 83/1385 biopsies of cancer patients over an 18 month period on which immunohistochemical staining (IHC) with ...
R, Lakhtakia, S K, Nema
openaire   +2 more sources

Clonal karyotype evolution involving ring chromosome 1 with myelodysplastic syndrome subtype RAEB-t progressing into acute leukemia [PDF]

, 2006
s Karyotypic evolution is a well-known phenomenon in patients with malignant hernatological disorders during disease progression. We describe a 50-year-old male patient who had originally presented with pancytopenia in October 1992.
Bennett JM, Bettina Wunderlich, Brigitte Poleck-Dehlin, Chen Z, Christoph Schmid, Cutler CS, De Witte T, Depil S, Georg Ledderose, Gisselsson D, Gullingsrud EO, Hans Jochen Kolb, Hebart H, Helga Schmetzer, Hoffmann WK, Hoffmeister PA, Holler E, Johann Mittermüller, Johansson B, Jotterand M, Kern W, Kolb HJ, Kolb HJ, Massenkeil G, Mattano, Mhawesch P, Mittermuller J, Moss PA, Mufti GJ, Rothe G, Sanders JE, Schmetzer H, Schmetzer H, Schmetzer HM, Schmid C, Seabright M, Seber A, Slovak ML, Sole F, Sole F, Thomas Duell, Tichelli A, Tichelli A, van Esser JW, Xu J, Yan J, Yoshida A   +46 more
core   +1 more source

Routine use of ancillary investigations in staging diffuse large B-cell lymphoma improves the International Prognostic Index (IPI)

Journal of Hematology & Oncology, 2009
Background The International Prognostic Index (IPI) is used to determine prognosis in diffuse large B-cell lymphoma (DLBCL). One of the determinants of IPI is the stage of disease with bone marrow involvement being classified as stage IV.
Shadbolt Bruce, Talaulikar Dipti, Dahlstrom Jane E, McDonald Anne   +3 more
doaj   +1 more source

The Effects of Immunophenotyping with Flow Cytometry on Prognosis in Acute Lymphoblastic Leukemia

Journal of Contemporary Medicine, 2021
Background: The identification of immunophenotype subgroups is very important for the diagnosis and prognosis of acute lymphoblastic leukemia(ALL). Material and Methods: The study included 105 children with ALL(65 males, 40 females; mean age 5.9±3.8 ...
Yesim Oymak, Dilek İnce, Raziye Vergin, Fearh Genel, Sultan Aydin Köker   +4 more
doaj   +1 more source

Immunophenotyping of Childhood Acute Lymphoblastic Leukemia in Qazvin City, Iran: A Cross-Sectional Study

The Journal of Qazvin University of Medical Sciences, 2023
Background:Acute lymphoblastic leukemia (ALL) is the most prevalent childhood cancer. ALL is a heterogeneous type of malignancy and treatment protocols vary based on the immunological classification of ALL.
Majid Vafaie, Mohammad Derhami1, Hamid Sadeghi, Saeideh Gholamzadeh Khoei   +3 more
doaj   +1 more source