Results 141 to 150 of about 1,268 (176)
Cystic fibrosis carriers have higher neonatal immunoreactive trypsinogen values than non-carriers [PDF]
American Journal of Medical Genetics, Part A, 2005 AbstractFollowing cystic fibrosis (CF) neonatal screening implementation, a high frequency of heterozygotes has been reported among neonates with elevated immunoreactive trypsinogen (IRT) and normal sweat chloride levels. We studied the relationship between normal IRT values and CF heterozygosity: 10,000 neonates were screened for CF by IRT measurement
exaly +4 more sources
Different patterns in immunoreactive anionic and cationic trypsinogen in urine and serum in human acute pancreatitis [PDF]
International Journal of Pancreatology: Official Journal of the International Association of Pancreatology, 1999 Acute pancreatitis (AP) results in elevated concentrations of trypsinogen (T) isoenzymes in serum. Immunoreactive anionic trypsinogen in urin (irAT/u) is elevated in AP, and has recently been proposed as a rapid diagnostic instrument and severity predictor.
A Borgström +2 more
exaly +6 more sources
Immunoreactive trypsinogen in healthy newborns and infants with cystic fibrosis [PDF]
Archives of Disease in Childhood - Fetal and Neonatal Edition, 2022 Objective Newborn screening (NBS) for cystic fibrosis (CF) was introduced in Switzerland in 2011 based on an immunoreactive trypsinogen (IRT)-DNA-IRT protocol. CF diagnosis was confirmed by sweat test and/or genetics but remained inconclusive for some newborns (cystic fibrosis transmembrane conductance regulator ...
Ralph Fingerhut +7 more
openaire +3 more sources
The Ontogeny of Serum Immunoreactive Pancreatic Lipase and Cationic Trypsinogen in the Premature Human Infant [PDF]
Biology of the Neonate, 2009 We evaluated the development of the exocrine pancreas in 16 healthy preterm infants (29.3 ± 1.6 weeks). The infants were fed breast milk with formula supplements (n = 8) or formula alone (n = 8). Growth was monitored weekly for 12 weeks then at 3, 6, 9, 12 months. At the same intervals sera were determined for pancreatic lipase and cationic trypsinogen.
Cleghorn, G +3 more
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Age-related alterations in immunoreactive pancreatic lipase and cationic trypsinogen in young children with cystic fibrosis [PDF]
The Journal of Pediatrics, 1985 Serum immunoreactive pancreatic lipase and cationic trypsinogen are elevated in young infants with cystic fibrosis (CF) and may be useful neonatal screening tests for CF. We compared lipase measured by a recently developed ELISA immunoassay with trypsinogen measured by radioimmunoassay in 70 children (ages 0.1 to 9.9 years) with CF who had various ...
Cleghorn, G +5 more
openaire +6 more sources
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Acta Paediatrica, International Journal of Paediatrics, 1999
Newborns with cystic fibrosis (CF) have increased blood immunoreactive trypsinogen concentrations. When screening for CF in the newborn by immunoreactive trypsinogen measurement, an abnormally high proportion of healthy ΔF508 carriers is found among false‐positive neonates, suggesting that a relationship could exist between immunoreactive trypsinogen ...
I, Lecoq +4 more
exaly +3 more sources
Newborns with cystic fibrosis (CF) have increased blood immunoreactive trypsinogen concentrations. When screening for CF in the newborn by immunoreactive trypsinogen measurement, an abnormally high proportion of healthy ΔF508 carriers is found among false‐positive neonates, suggesting that a relationship could exist between immunoreactive trypsinogen ...
I, Lecoq +4 more
exaly +3 more sources
Clinical Transplantation, 1999
The aim of this study was to evaluate pancreatic function in total parenteral nutrition (TPN)‐dependent children with permanent intestinal failure by measuring immunoreactive trypsinogen (IRT) levels. Between 1992 and 1996, 105 pediatric patients with permanent intestinal failure were referred to the Children's Hospital of Pittsburgh for small ...
Jorge Reyes, L Sigurdsson
exaly +3 more sources
The aim of this study was to evaluate pancreatic function in total parenteral nutrition (TPN)‐dependent children with permanent intestinal failure by measuring immunoreactive trypsinogen (IRT) levels. Between 1992 and 1996, 105 pediatric patients with permanent intestinal failure were referred to the Children's Hospital of Pittsburgh for small ...
Jorge Reyes, L Sigurdsson
exaly +3 more sources
Immunoreactive trypsinogen levels in infants with cystic fibrosis complicated by meconium ileus
Screening: Journal of the International Society of Neonatal Screening, 1993Abstract To examine abnormalities in immunoreactive trypsinogen (IRT) in infants with cystic fibrosis (CF) and meconium ileus (MI) and to evaluate the utility of IRT as a diagnostic aid in MI, we compared IRT in 19 infants with CF and MI to values in normal infants and in 91 infants with CF without MI.
Ronald Sokol +2 more
exaly +2 more sources
Sweat chloride and immunoreactive trypsinogen in infants carrying twoCFTRmutations and not affected by cystic fibrosis [PDF]
Archives of Disease in Childhood, 2016 Newborns with raised immunotrypsinogen levels who have non-pathological sweat chloride values and carry two cystic fibrosis transmembrane regulator (CFTR) mutations of which at least one is not acknowledged to be cystic fibrosis (CF)-causing are at risk of developing clinical manifestations consistent with CFTR-related disorders or even CF.
Castellani, Carlo +3 more
openaire +3 more sources
Diagnostic dilemmas resulting from the immunoreactive trypsinogen/DNA cystic fibrosis newborn screening algorithm [PDF]
The Journal of Pediatrics, 2005 To quantitate the proportion of infants identified through cystic fibrosis (CF) newborn screening (NBS) by an immunoreactive trypsinogen (IRT)/DNA screening algorithm who have an unclear diagnosis as defined by the findings of an elevated IRT level and either 1) 2 CF gene (CFTR) mutations detected and sweat chloride level or=30 and
Parad, Richard B., Comeau, Anne Marie
openaire +4 more sources