Results 31 to 40 of about 1,268 (176)

Cystic fibrosis diagnosed by state newborn screening: Or is it?

SAGE Open Medical Case Reports, 2020
Newborn screening for cystic fibrosis is universal across the United States; however, each state chooses the method by which they screen. Illinois employs a two-step process which includes the measurement of the immunoreactive trypsinogen followed by an ...
Maura Fox, Angelique Mercier, Adrienne Savant, Theresa A Laguna   +3 more
doaj   +1 more source

Neonatal Screening for Cystic Fibrosis in Hungary—First-Year Experiences

International Journal of Neonatal Screening, 2023
The aim of this study is to evaluate the strategy of the cystic fibrosis newborn screening (CFNBS) programme in Hungary based on the results of the first year of screening.
Andrea Xue, István Lénárt, Judit Kincs, Hajnalka Szabó, Andrea Párniczky, István Balogh, Anna Deák, Péter Béla Monostori, Krisztina Hegedűs, Attila J. Szabó, Ildikó Szatmári   +10 more
doaj   +1 more source

Diagnostic and Communication Challenges in Cystic Fibrosis Newborn Screening

Life, 2023
As of December 2009, cystic fibrosis (CF) newborn screening (NBS) is performed in all 50 US states and the District of Columbia. Widespread implementation of CF newborn screening (CFNBS) in the US and internationally has brought about new and varied ...
Joan Kathleen DeCelie-Germana, Lynn Bonitz, Elinor Langfelder-Schwind, Catherine Kier, Barry Lawrence Diener, Maria Berdella   +5 more
doaj   +1 more source

Identification of two major proteins of bovine pancreatic stones as immunoreactive forms of trypsinogens [PDF]

Biochemical Journal, 1982
Two major proteins have been identified in sodium citrate extracts of bovine pancreatic stones from 15 glands with lithiasis. They were found to have a molecular weight of about 24 000 and were further characterized by a variety of methods, including polyacrylamide-gel electrophoresis in the presence of sodium dodecyl sulphate, isoelectric focusing ...
A, De Caro, L, Multigner, H, Vérine
openaire   +2 more sources

Pancreatitis-Associated Protein in Neonatal Screening for Cystic Fibrosis: Strengths and Weaknesses

International Journal of Neonatal Screening, 2020
There are currently four countries and one local region in Europe that use PAP in their newborn screening programme. The first country to employ PAP at a national level was the Netherlands, which started using IRT/PAP/DNA/EGA in 2011. Germany followed in
Olaf Sommerburg, Jutta Hammermann
doaj   +1 more source

Age-Related Alterations of Immunoreactive Pancreatic Cationic Trypsinogen in Sera From Cystic-Fibrosis Patients with and Without Pancreatic Insufficiency [PDF]

, 1986
Serum immunoreactive cationic trypsinogen levels were determined in 99 control subjects and 381 cystic fibrosis (CF) patients. To evaluate the status of the exocrine pancreas all CF patients had previously undergone fecal fat balance studies and/or ...
M L Corey, Forstner, G.G., Corey, M.L., D J Moore, Moore, D.J., G G Forstner, Corey, ML, K J Gaskin, P R Durie, Wong, SS, Moore, DJ, Cleghorn, GJ, G J Cleghorn, Cleghorn, G.J., Gaskin, KJ, Wong, S.S., Gaskin, K.J., Forstner, GG, Durie, P.R., S S Wong, Durie, PR   +20 more
core   +1 more source

Molecular size distribution of immunoreactive trypsin and renal tubular dysfunction: Role in trypsin plasma-urine transfer [PDF]

, 1987
In order to investigate the role of circulating free trypsinogen and renal tubular dysfunction in affecting trypsin plasma-urine transfer, serum immunoreactive trypsin (IRT), its urinary output, IRT molecular size distribution, filtrable immunoreactive ...
FABRIS C., BASSO D., CAVALLINI G., BENINI L., VANTINI I., PICCOLI, ANTONIO, DEL FAVERO G., TONON M., BONVICINI P., BROCCO G.   +9 more
core   +3 more sources

Performance of a Three-Tier (IRT-DNA-IRT) Cystic Fibrosis Screening Algorithm in British Columbia

International Journal of Neonatal Screening, 2020
Newborn screening for Cystic Fibrosis has been implemented in most programs worldwide, but the approach used varies, including combinations of immunoreactive trypsinogen (IRT) and CFTR mutation analysis on one or more specimens. The British Columbia (BC)
Graham Sinclair, Vanessa McMahon, Amy Schellenberg, Tanya N. Nelson, Mark Chilvers, Hilary Vallance   +5 more
doaj   +1 more source

Cystic Fibrosis: 15 Years of Experience in Newborn Screening in Uruguay [PDF]

Journal of Inborn Errors of Metabolism and Screening
Cystic fibrosis (CF) is a severe autosomal recessive genetic disorder caused by variants in the CFTR gene, affecting multiple organ systems, primarily the respiratory and digestive tracts.
María B. Mancebo, María E. Machado, María S. Méndez, Paola Audicio, Graciela Queiruga, Cecilia Queijo   +5 more
doaj   +2 more sources

Neutrophil lymphocyte ratio, mean platelet volume, and immunoreactive trypsinogen as early inflammatory biomarkers for cystic fibrosis in infancy: A retrospective cohort study [PDF]

, 2023
BackgroundAirway inflammation starts in early life in cystic fibrosis (CF) and limited, objective markers are available to help identify infants with increased inflammation. We aimed to investigate neutrophil, lymphocyte ratio (NLR), mean platelet volume
Kunt, Nursima, Ayse Tana Aslan, Pelin Asfuroglu, ŞİŞMANLAR EYÜBOĞLU, TUĞBA, Ali Ersoy, Unal, Gokcen, Tuğba Şişmanlar Eyuboglu, Sevgi Pekcan, Gokcen Unal, Mehmet Kose, KUNT BAYKAL, NURSİMA, KÖSE, MEHMET, Eyuboglu, Tugba Sismanlar, ASLAN, AYŞE TANA, Pekcan, Sevgi, ASFUROĞLU, PELİN, Nursima Kunt, ERSOY, ALİ   +17 more
core   +1 more source