Results 161 to 170 of about 30,806 (226)

Engineered microvesicle-mediated multimodal therapy resolves ulcerative colitis via synergistic immunoregulation, barrier restoration, and microbiota remodeling. [PDF]

Mater Today Bio
Qi C, Liang C, Wang S, Zhang H, Wei H, He X, Chen W.   +6 more
europepmc   +1 more source

Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine

MedComm, Volume 7, Issue 10, October 2026.
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song, Epiphane K. Silli, Yazhen Xu, Huixia Lv, Ruoxian Song   +4 more
wiley   +1 more source

Fumarate and Its Esters: Physiology, Pathology, Molecular Mechanisms, Diseases, and Therapy

MedComm, Volume 7, Issue 10, October 2026.
Fumarate is an endogenous immunometabolite that regulates metabolism, redox homeostasis, and inflammation. Although fumaric acid esters (FAEs) share several molecular targets with fumarate, their distinct physicochemical properties confer unique biological activities and therapeutic applications.
Peng Zhu, Mengling You, Yi Zeng, Jinglin Zhang, Si Chen, Rong Rong, Xiaobo Xia   +6 more
wiley   +1 more source

Herbal Formula AC591 Protects Against Cisplatin‐Induced Hearing Loss by Inhibiting p53‐Mediated Ferroptosis

Smart Medicine, Volume 5, Issue 5, October 2026.
AC591 and its core active component 18β‐glycyrrhetinic acid effectively alleviate cisplatin‐induced ototoxicity by binding p53 and suppressing p53‐mediated ferroptosis, representing promising agents for preventing cisplatin‐related hearing loss. ABSTRACT Cisplatin is a widely utilized chemotherapeutic agent for the treatment of malignant cancers ...
Yunhao Wu, Yu Tao, Lin Wei, Qiuping Liu, Jiaxin Liu, Wen Jiang, Weiwei Shi, Peng Cao, Xiaolong Fu, Cheng Cheng   +9 more
wiley   +1 more source

Associations Between Gut Microbiota and Immune Profiles in Community‐Dwelling Older Adults and the Regulatory Role of Polygonatum odoratum

Aging Cell, Volume 25, Issue 10, October 2026.
Gut Microbiota‐Immune Associations in Community‐Dwelling Older Adults: Role of Polygonatum odoratum. ABSTRACT Aging is often associated with intestinal microbiota imbalance and immune system degeneration. The dysregulation and crosstalk of these two factors markedly elevate the elderly's susceptibility to infections and age‐related diseases ...
Tingting Xia, Hongmei Wu, Tianyi Cui, Wenzhi Yang, Min Zhang, Yuhong Huang, Shengyuan Zhou, Yongsheng Wu, Donglan Yan, Fan Jia, Lin Zhang, Zhi Cui, Jiayao An, Xinqin Zhong, Bin Lv, Xin Zhao, Kaijun Niu, Xiumei Gao   +17 more
wiley   +1 more source

Thymectomy with or without maintenance therapy for myasthenia gravis patients: a tri-center, real-world study. [PDF]

Ther Adv Neurol Disord
Zhang H, Fan M, Shi Y, Huang X, Cui Y, Yu Z, Yang CS, Li HN, Zhang XH, Liu P, Wu T, Shi FD, Qi GY.   +12 more
europepmc   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, Volume 81, Issue 10, Page 3439-3452, October 2026.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Safety, Immunovirologic, and Central Nervous System Effects of PD-1 Inhibition in People With HIV Without Malignancy. [PDF]

J Infect Dis
Reoma LB, Johnson TP, Cheung K, Smith BR, Pérez L, Wiebold A, Migueles SA, Connors M, Boritz EA, Zahid M, Lai C, Gill J, Shah S, Lyndaker A, Burbelo PD, Maldarelli F, Lane HC, Shin J, Hammoud DA, Nair G, Nath A.   +20 more
europepmc   +1 more source

Ovarian Cancer‐Associated Ascites Accumulates NK Lymphocytes Displaying a Transcriptomic Profile Consistent With the Immature/Secretory CD56bright Subtype

Immunology &Cell Biology, Volume 104, Issue 9, Page 896-905, October 2026.
NK cells present in EOC‐associated ascites retain elements of the conventional NK cell program while displaying a transcriptional profile distinct from peripheral blood NK cells. This profile encompasses biological programs usually associated with the CD56bright NK cell functions, which is consistent with transcriptional remodeling rather than complete
Caroline Natânia de Souza‐Araújo, Glenerson Baptista, Gabriela Rapozo Guimarães, Raissa Carolina Alves da Silva, Adriana Yoshida, Cláudia Rodrigues Tonetti, José Andrés Yunes, Daniela Maira Cardoso, Sophie Derchain, Mariana Boroni, Fernando Guimarães   +10 more
wiley   +1 more source

Regulatory Roles of Long Non-Coding RNAs in Methotrexate Pharmacology: Mechanistic and Translational Insights. [PDF]

Pharm Res
Guzmán-Martín CA, González-Moyotl NJ, Juárez-Vicuña Y, Bojalil R, Martínez-Martínez LA, Arenas-Díaz AL, Martínez-Rosas M, Peña-Peña M, Vázquez-Toledo MA, Romero-Nava R, Jiménez-Ortega RF, Hidalgo-Bravo A, Velázquez-Cruz R, Sánchez-Muñoz F.   +13 more
europepmc   +1 more source